CorePlus, a high complexity CLIA-certified clinical and anatomic pathology laboratory, says it has diagnosed over 10,000 cases using Ibex’s AI-powered cancer diagnostics platform, Galen. To boost patient outcomes, pathologists used AI-driven insights from Galen to correct the diagnosis of over 150 patients.

CorePlus was one of the first labs in North America to deploy an AI-powered pathology solution, implementing Ibex’s Galen Prostate for before-sign-out quality control, and then expanded its capabilities to include Galen Breast in the diagnosis of breast biopsies, the organization said. Following the successful rollout of both technologies, used to analyze more than 125,000 pathology slides, CorePlus expanded deployment and its pathologists now use Galen during primary diagnosis, benefiting from AI-powered insights for triage, detection of cancer and other morphologic features, grading, and reporting. Moreover, the expansion also drives efficiency gains as Galen helps to streamline lab processes and reporting.

“Ibex’s robust AI platform has brought greater confidence to our pathologists, providing continuously accurate insights and enabling us to support referring urologists with more accurate and objective diagnostic reports,” says Juan C. Santa Rosario, MD, chief medical officer at CorePlus. “Our use of Ibex’s technology in primary diagnosis enables our pathologists to operate more efficiently at a greater scale and helps us significantly reduce turnaround time to keep up with growing demand.”

Further reading: Ibex Launches Galen Breast HER2 to Support Breast Cancer Biomarker Scoring

Galen supports CorePlus pathologists in the diagnosis of breast and prostate biopsies by helping them identify cancer, determine the cancer grading and subtype, and detect multiple other malignant and non-malignant morphological features, the company says. Galen also helps pathologists prioritize cases and rapidly access areas of interest, as well as automating tasks such as reporting and tumor measurement. Galen is a widely deployed AI technology in pathology and is used as part of everyday clinical practice at laboratories, hospitals, and health systems worldwide. Galen demonstrated outstanding outcomes across multiple clinical studies performed on various tissue types and diagnostic workflows(1,2,3,4,5).

“Ibex is driving the future of cancer diagnosis, providing pathologists with the best tools to deliver accurate and timely diagnosis powered by AI,” says Joseph Mossel, co-founder and CEO of Ibex Medical Analytics. “I am delighted to see CorePlus leading the way in adoption, demonstrating how patient outcomes can be improved through the implementation of AI for primary diagnosis. We remain focused on bringing our AI platform to labs around the world to help pathologists reach zero misdiagnoses in cancer, and CorePlus demonstrates how this is achievable.”

References:

  1. Pantanowitz et al., An artificial intelligence algorithm for prostate cancer diagnosis in whole slide images of core needle biopsies: a blinded clinical validation and deployment study, THE LANCET Digital Health Aug 2020
  2. Sandbank et al., Validation and real-world clinical application of an artificial intelligence algorithm for breast cancer detection in biopsies; npj Breast Cancer 8, 129 (2022)
  3. Comperat et al., Clinical Level AI-Based Solution for Primary Diagnosis and Reporting of Prostate Biopsies in Routine Use: A Prospective Reader Study, European Congress of Pathology 2021
  4. Raoux et al., Novel AI-Based Solution for Supporting Primary Diagnosis of Prostate Cancer Increases the Accuracy and Efficiency of Reporting in Clinical Routine, USCAP 2021
  5. Sandbank et al., Validation and Clinical Deployment of an AI-Based Solution for Detection of Gastric Adenocarcinoma and Helicobacter pylori in Gastric Biopsies, USCAP 2022