Aalto Bio Reagents, Dublin, Ireland, has launched a mouse monoclonal antibody to Helicobacter pylori flagellin. H. pylori is, a gram-negative bacterium living in the mucus of the human digestive tract. It is a ubiquitous organism that is present in 50% of the global population. However, it can lead to a variety of such serious upper gastrointestinal disorders as chronic gastritis, gastric cancer, and peptic ulcer disease. Diagnosis of infection is accomplished by noninvasive methods, such as detection of H. pylori antigens in stool samples or by determination of IgA, IgG, or IgM antibodies to H. pylori in human serum samples. The monoclonal antibody to H. pylori flagellin is self-pairing and can be used as both capture and label elements in immunoassay development. For more information, visit Aalto Bio Reagents.
