Qiagen, Hilden, Germany, has partnered with 10X Genomics, Pleasanton, Calif, to develop and promote comprehensive systems for next-generation sequencing (NGS), single-cell biology, and bioinformatics.

The collaboration will optimize Qiagen’s sample technologies, including the MagAttract HMW DNA kit, for use with 10x Genomics GemCode and Chromium systems. The companies also aim to support complete workflows in single-cell biology by leveraging 10x Genomics’ GemCode technology with Qiagen’s single-cell biology portfolio and QiaSeq NGS solutions.

The partners also plan to investigate the implementation of 10x Genomics’ GemCode technology with Qiagen’s proprietary GeneReader NGS system. As a result, Qiagen’s sample-to-insight solutions for NGS will be upgraded to allow customers to detect structural variants, haplotypes, and other valuable long-range information from DNA inputs as little as 1 ng.

Other activities will include enabling the processing and analysis of 10x Genomics’ “linked-reads” with Qiagen’s suite of leading bioinformatics solutions, in an effort to address the challenges of data analysis, interpretation, clinical decision-support, and reporting that rely on testing for long-range phasing and structural variants in genomics. The companies will further co-market each other’s applications.

Peer Schatz, Qiagen.

Peer Schatz, Qiagen.

“Qiagen’s collaboration with 10x Genomics enables both companies to better serve its customers, helping them make groundbreaking advances in single-cell biology, bioinformatics and beyond,” says Peer Schatz, CEO of Qiagen. “10x Genomics is recognized for delivering critical long-range sequence information that greatly expands the quality of genome research. This partnership will further the potential of each of our product lines while providing significant new capabilities to NGS researchers.”

Serge Saxonov, 10x Genomics.

Serge Saxonov, 10x Genomics.

“We welcome the opportunity to partner with Qiagen, with its comprehensive offerings for genomic analysis, ranging from sample preparation technologies to bioinformatics solutions for the interpretation and analysis of genomic data,” says Serge Saxonov, CEO, 10x Genomics. “Access to long-range sequence information is becoming the standard for obtaining the most comprehensive understanding of disease, and we expect this collaboration to allow our respective customers to gain valuable insights that have previously not been possible.”

10x Genomics’ GemCode platform is designed to overcome existing NGS limitations through a combination of microfluidics, chemistry, and bioinformatics. The molecular barcoding and analysis system consists of instrumentation, reagents, and software for a broad range of applications, including single-cell transcriptomics and whole genome analysis.

For more information, visit Qiagen and 10X Genomics.