The Autokit Lp(a) test kit is for the quantitative determination of lipoprotein(a) in serum and plasma to aid with the risk assessment of coronary disease.
The assay utilizes turbidimetric immunoassay methodology in a simple, one-step direct determination with high specificity, no reactivity to Apo B or Plasminogen and stability.
When sample is mixed with buffer and the antibody, Lp(a) in the sample combines specifically with anti-human lipoprotein(a) antibodies in the reagent to yield an insoluable aggregate that causes increased turbidity. The degree of turbidity can be measured optically and is proportional to the amount of Lp(a) protein mass in the sample.
The within-run precision has less than 3%CV. The linear range of the assay is 1 to 100 mg/dL. Studies have been conducted that provide expected value cutoff values for both Caucasian and African-American populations. Applications are available for most chemistry analyzers.
Keyword: lipoprotein(a), test