The optimized protocols on SPT Labtech’s firefly+ platform use Agilent’s SureSelect Max DNA Library Prep Kit for clinical research and precision medicine applications.
SPT Labtech and Agilent Technologies have introduced automated target enrichment protocols designed to streamline genomic workflows for clinical research, oncology, and precision medicine applications.
The optimized protocols run on SPT Labtech’s firefly+ platform and support researchers using Agilent’s SureSelect Max DNA Library Prep Kits. Available immediately to all firefly+ users through the firefly community cloud, the protocols enable automated library preparation with Agilent’s Library Prep and Target Enrichment panels.
The collaboration between SPT Labtech’s applications team and Agilent’s R&D and product teams focused on development work using Agilent’s Exome V8 and a smaller panel. The protocols are applicable across Agilent’s full range of Target Enrichment panels, providing laboratories with a streamlined workflow option.
By leveraging firefly+ automation, the protocols enable hands-off library preparation with increased reproducibility, reduced error rates, and time savings compared to manual processes.
“Making these protocols available today is a critical step in addressing bottlenecks across sequencing workflows. By combining Agilent’s gold-standard chemistry with firefly+ automation, we are helping labs scale sequencing faster, more reliably, and with greater efficiency,” says Morten Frost, chief commercial officer at SPT Labtech, in a release.
The automated approach addresses common challenges in genomic workflows where manual library preparation can introduce variability and consume significant technician time. Target enrichment protocols are essential for focusing sequencing efforts on specific genomic regions of interest, particularly in clinical applications where precise detection of variants is critical.
“Agilent’s SureSelect Max DNA Library Prep Kit delivers the robust chemistry and high performance that labs demand for target enrichment. We are pleased to partner with SPT on enabling the Target Enrichment protocol on the firefly+, enabling researchers to scale their sequencing workflows with greater efficiency,” says Nina Green, vice president and general manager of the Clinical Diagnostic Division at Agilent, in a release.
The protocols support high-throughput sequencing applications across multiple research areas, including oncology studies where comprehensive cancer panels help identify actionable mutations and precision medicine initiatives that require reliable detection of genetic variants.
SPT Labtech representatives will demonstrate the new protocols at the American Society of Human Genetics annual meeting, Oct 14-18 in Boston, at booth 2487.
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