Nucleic acid separation system
Qiagen, Valencia, Calif, introduces QIAxcel, an automated system for nucleic acid separation that is designed to take the place of traditional slab-gel analysis. It uses ready-to-go gel cartridges that allow samples to be prepared with minimal hands-on interaction, reducing manual handling errors and avoiding exposure to toxic reagents. The system analyzes up to 96 samples per run; and 12 protocols can be performed in 5 minutes. It is characterized by detecting concentrations of nucleic acids as small as 0.1 ng/µL. Preprogrammed protocols, in combination with corresponding gel cartridges, allow separation and analysis of nucleic acids, such as singleplex or multiplex PCR fragments, DNA digested with restriction endonucleases, synthesized oligonucleotides, total RNA, and complementary RNA. The detection sensitivity of system’s analyzer facilitates reproducible results, even with low nucleic acid concentrations. With its resolution as low as 3 to 5 bp, the new instrument delivers greater accuracy than slab-gel analysis. The dimensions are 36.2 cm x 38.1 cm x 55.9 cm/23 kg. The instrument is intended to be used only in combination with QIAxcel kits for applications described in the respective handbooks; the kits are intended for research only and are not for use in diagnostic procedures.