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| William E. Kraus, MD |
LipoScience Inc, Raleigh, NC, has entered into a research agreement with Duke University School of Medicine, Durhan, NC, in an effort to identify cardiovascular risk factors that can be used alone or in combination with other clinical measures to improve stratification and management of acute coronary syndrome.
The agreement encompasses studies to be performed with Duke’s CATHGE (CATHeterizationGENetics) and other patient registries.
“Through this collaboration, LipoScience will gain access to a large patient registry and will work with leading researchers in the field to investigate the clinical utility of the NMR LipoProfile® test,” says “Under the terms of the agreement, LipoScience will perform NMR LipoProfile test analysis and other metabolite assays of blood samples from the registries to learn more about the relationship between lipoproteins and acute coronary syndrome in these patient populations.”
“Currently available clinical diagnostic tests provide imprecise measures of cardiovascular risk, particularly with respect to acute coronary events,” says William E. Kraus, MD, professor of medicine at Duke University Medical Center. “Also, functional studies are similarly relatively imprecise with respect to diagnostic information regarding moderately severe coronary artery disease.
“Development of ancillary and complementary information isof prime interest in clinical cardiology,” Kraus adds. “The purpose of this research is to investigate how cardiovascular risk genes, biochemical markers, and currently available cardiovascular functional studies improve the way cardiovascular disease is diagnosed, predicted, and managed.”
Through the collaboration, LipoScience will gain access to a large patient registry and will work with leading researchers in the field to investigate the clinical utility of the NMR LipoProfile test, according Ray Pourfarzib, PhD, vice president, medical affairs, LipoScience.
The CATHGEN registry was collected between 2001 and 2011 to create a significant combined biochemical and clinical bio- and data repositories for cardiovascular disease research. The data repository contains genetic information, blood biochemical marker data, clinical information, and clinical endpoint follow-up.
[Source: LipoScience]
