BostonGene, a provider of AI-driven, molecular and immune profiling solutions, and Exigent Research, an independent community oncology research network, announced a new study, designed to demonstrate the clinical benefits of using BostonGene Tumor Portrait test for advanced cancer patients in a community setting.
The “BostonGene and Exigent Genomic INsight” (BEGIN) study will validate improved patient outcomes by tailoring treatments based on combined WES and RNA-seq coupled with AI-powered analytics.
Exigent Research was formed from a partnership between the Quality Cancer Care Alliance (QCCA) and the National Cancer Care Alliance (NCCA), radically accelerating progress in cancer research with a unique network-based model. Exigent is committed to providing patients access to the best and most innovative trials in their communities while advancing collective oncology knowledge across its network of over 185 sites and 660 providers.
“Partnering with BostonGene represents a critical milestone for us. Leveraging their next-generation sequencing expertise to deliver data-driven results has the potential to be a real asset for our providers and patients,” says Sibel Blau, MD, president and CEO at Exigent Research and Medical Director at Northwest Medical Specialties. “This strategic partnership is built on BostonGene’s innovative solutions and deep expertise in AI-based molecular and immune profiling to improve treatment options.”
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As part of the BEGIN study, BostonGene will perform comprehensive analysis using the BostonGene Tumor PortraitTM test, including DNA whole exome (WES) and RNA transcriptome (RNAseq) sequencing, on patient tumor samples from participating Exigent sites. The study aims to determine the utility and frequency of actionable findings identified by a comprehensive sequencing approach in advanced cancer patients in a real-world setting. The trial will also assess the impact of the BostonGene Tumor PortraitTM test findings on treatment decisions and its impact on several value-based care metrics.
“This collaboration marks an important step in our mission to bring precision medicine, today mostly available in academia, into community practices where most patients are seen,” says Nathan Fowler, MD, chief medical officer at BostonGene. “We believe that this partnership will underscore the power of next-generation multiomics AI-driven solutions to positively impact patient outcomes in community setting.”