Point-of-care Blood Glucose Monitoring System
Measures and corrects hematocrit and electrochemical interferences
An advanced, patented* new blood glucose monitoring system from Nova Biomedical elevates bedside glucose testing to a new level of analytical performance that approaches the quality of central laboratory testing. The Nova StatStrip™ point-of-care glucose monitor incorporates new four-well glucose measuring strip technology. Current glucose strips use only one well. Nova’s Multi-Well™ system measures and corrects hematocrit interference as well as interferences from acetaminophen (Tylenol), uric acid, ascorbic acid (Vitamin C), maltose, galactose, xylose, and lactose. StatStrip also eliminates oxygen interference to provide accurate glucose results regardless of the sample’s oxygen status. In addition, these strips require no calibration coding, avoiding another potential source of error. An incorrect input of a calibration code can change the reported glucose value by up to 40%. These analytical improvements are particularly important to hospitals that are following the new tight glycemic control protocols for diabetic patients. Interferences generated by current technology strips result in higher than actual glucose readings, leading to the potential of overdosing insulin and creating hypoglycemia. StatStrip’s 6-second analysis time, color touch-screen operation, and simple operating steps make bedside glucose testing fast and easy for point-of-care staff. Its small, 1.2-µL sample size results in easy sample acquisition and minimal pain for the patient. Comprehensive instrument manager software provides management, control, and regulatory compliance, and allows the StatStrip system to be completely customized to the needs of each department within the hospital.
Nova Biomedical
(781) 647-3700; www.novabio.com


Hazardous Material Shippers
For medical specimen samples
Infekta Packaging International has introduced a complete product line of ambient specimen packaging for the shipment of infectious and diagnostic medical specimens that comply with all regulations under class 6.2. The company’s products conform to applicable regulations for shipping medical specimens, including UN/ICAO, US DOT, IATA, CDC, and USPS. DIAGNA-PAK offers a variety of different ambient packages to ship diagnostic medical specimens by land, air, or US Mail. Each package configuration has a secondary vessel that is 95 KPA tested. The secondary containers of this line include plastic screw-cap bottles that fit inside fiberboard screw-cap mailing tubes or a unique and patented 95 KPA polybag with the absorbent material already laminated to the inside of each bag. Each one of these bags fit diagonally (corner to corner) inside a preprinted box. INFEKTA-PAK is a combination package line of shippers for the transport of infectious medical specimens (all risk groups). Every product in this group features a preprinted outer box with all appropriate markings for shipping infectious samples. Users simply complete the declaration form and attach it to the package.
Infekta Packaging International
(866) 847-4413; www.infekta.com


Lipase Reagent
Without serum matrix effects
Stanbio Laboratory has released a reagent test to measure lipase in serum or plasma on the SIRRUS® benchtop clinical chemistry analyzer. This enzymatic, colorimetric method uses a synthetically produced lipase substrate in a microemulsion that is specifically split by lipase in the presence of colipase and bile acids. The combination of lipase and bile acids makes this specific and reliable for pancreatic lipase without any reaction due to lipolytic enzymes or esterases. The reagent composition has been thoroughly optimized so there is no serum matrix effect. The generated methylresorufin-ester is spontaneously degraded to methylresorufin. The absorbance of this red dye is directly proportional to the lipase activity in the sample. Each reagent bottle can run 50 tests, is packaged six bottles per kit, and features 30-day onboard stability and 30-day calibration stability. Associated calibrator and controls are also available. SIRRUS is a fully automated benchtop chemistry analyzer capable of performing up to 400 tests per hour. Stanbio offers a broad menu of ready-to-use, bar-coded, liquid reagents and the flexibility to configure open-channel applications. Features such as reusable cuvettes, Windows®-based software, auto-rerun, and auto-dilution make it easy to learn and efficient to operate. SIRRUS also accepts bar-coded primary sample tubes and allows stat interruptions.
Stanbio Laboratory
(866) 782-6246; www.stanbio.com


Automated LDL Reagent
Direct measurement of LDL cholesterol
Equal Diagnostics Inc has introduced Liquid Select LDL, a homogeneous, completely automated direct LDL test for use on clinical chemistry analyzers. The Liquid Select LDL Direct Assay measures LDL cholesterol levels in serum or plasma directly, without the need for any offline pretreatment or centrifugation steps. Direct measurement of LDL cholesterol obviates the limitations of the Friedewald formula, which are the intrinsic variability in its multiple components, the potential source of error related to patient noncompliance with 12-hour fasting, and the potential interference from elevated triglyceride levels. This direct measurement has proved superior to the Friedewald formula in assessing LDL cholesterol values in diabetic patients. Because direct measurement of LDL cholesterol is still a recent concept for clinical laboratories, clinicians must regularly specify this test when sending patient samples out for processing. The Liquid Select LDL is available in two convenient test sizes: 100 tests and 800 tests. (Tests per kit are approximate.) Easy to set up applications are available for most automated chemistry systems. For high-volume analyzers that require priming of the reagent lines, the R1 and R2 components can be purchased separately. Equal Diagnostics provides data sheets and step-by-step instructions for setting up the Liquid Select LDL.
Equal Diagnostics Inc
(800) 999-6578; www.equaldiagnostics.com


Monoclonal Antibody to Melan-A
Stains paraffin tissue sections
BioGenex Melan-A antibody (clone A103) is designed for the specific localization of Melan-A or MART-1 in formalin-fixed, paraffin-embedded tissue sections used in IHC applications. Melan-A, a product of the MART-1 gene, is a differentiation antigen that is expressed in 100% of melanocytes, most melanomas, and 50% to 60% of melanoma cell lines. It was identified as one of the melanoma antigens recognized by autologous cytotoxic T cells, and as an antigenic target for tumor-infiltrating lymphocytes. Melan-A expression has been shown to disappear with time, and is inversely proportional to disease progression in a small percentage of subjects. It has been suggested that the loss of expression of these antigens is a defense mechanism the melanoma cell uses to escape surveillance. This antibody also stains Melan-A in normal melanocytes and in the retina. It does not stain normal or tumor tissues from nonmelanocyte lineages. BioGenex offers Melan-A antibody in concentrated form and as a ready-to-use reagent for manual use and for use on BioGenex automated staining systems. The antibody has been optimized for use with the BioGenex Super Sensitive™ Ready-to-Use Detection Systems.
BioGenex
(800) 421-4149; www.biogenex.com


Data-Management Software Solution
Quality control for clinical diagnostics
Bio-Rad Laboratories Inc has released Unity Real Time™, a new software solution designed to improve the effectiveness of quality control data management in the clinical laboratory. Unity Real Time facilitates compliance with regulatory and accreditation requirements (such as ISO 15189 and CLIA) and helps meet the quality demands of the clinical laboratory. The system can be easily integrated with existing laboratory information systems and laboratory instruments to consolidate quality control data management into one consistent platform. Unity Real Time provides high-quality statistical process control with comprehensive audit trails, facilitates run-time and supervisory data review, offers advanced charts and reports for data analysis, and monitors ongoing performance of quality-control rules with analytical goal options. Unity Real Time also enables participation in the Unity Interlaboratory Program to compare laboratory QC results against the largest peer groups in the clinical diagnostics industry. Unity Real Time can be used with the patented Westgard Advisor™ add-on module to automatically recommend and implement optimal QC rules for each test. By establishing proper quality-control design, the module helps the lab decrease false rejections and attain desired quality goals with the highest error-detection rate possible. This reduces desensitization to false error flags, and ultimately saves time and money by eliminating unnecessary troubleshooting and repeat testing.
Bio-Rad Labs Inc
(800) 2-BIO-RAD; www.bio-rad.com.


Automated Pipetting Systems
Offer application flexibility and accuracy
Eppendorf epMotion automated pipetting systems offer application flexibility and pipetting accuracy at an affordable price. With four models starting at $19,995, there’s an epMotion that fits application needs from cell biology to molecular biology to chemistry. Features include a 4 to 12 deck that accommodates single tubes to 384-well plates, accuracy from 5% CV at 1 µL—precise enough for exquisitely reproducible qPCR—and certified tools that come with a 2-year warranty. Designed for user-friendliness and convenience, setup and training takes less than 1 day.
Eppendorf
(800) 645-3050; [removed]www.eppendorfna.com/ARTSautomation[/removed]


Antibody to Anti-Human Progesterone Receptor
Stains paraffin tissue sections
BioGenex Anti-Human Progesterone Receptor (clone PR88) is designed for the specific localization of Progesterone Receptor in formalin-fixed, paraffin-embedded tissue sections used in IHC applications. The determination of steroid hormone receptors has become widely used in the management of hormone-dependent cancers. The presence of progesterone receptor in human breast cancer has been proposed as a mechanism whereby tumor cells respond to estrogen, and its presence may therefore serve as a marker for enhanced estrogen responsiveness. The most recent methods of receptor detection involve immunohistochemical techniques that use monoclonal antibodies directed against both the estrogen and the progesterone receptors. Historically, estrogen receptor-positive/progesterone receptor-positive breast carcinoma patients have demonstrated a better response to endocrine therapy than estrogen receptor-positive/ progesterone receptor-negative patients. The use of monoclonal antibodies to determine progesterone-receptor status increases the predictive value of immunohistochemical analysis with respect to the response of human tumors to hormonal modulation. BioGenex offers Progesterone Receptor antibody in concentrated form and as a ready-to-use reagent for manual use and for use on BioGenex automated staining systems. The antibody has been optimized for use with the BioGenex Super Sensitive™ Ready-to-Use Detection Systems.
BioGenex
(800) 421-4149; www.biogenex.com


Stereo Microscope Series
Offers large zoom ratio and high resolution
Stereo microscope users can see more detail, capture more image information, and work more comfortably than before with the Olympus SZX2 series of stereo microscopes. The series, which Olympus has completely redesigned using the input of researchers worldwide, offers the largest zoom ratio (16.4:1) and the highest resolution available in a life science stereo microscope. There are two microscopes in the series: the SZX16, for research stereo fluorescence and other high-level life-science applications; and the SZX10, for both advanced and standard research requirements such as selecting and sorting specimens. The SZX16 research stereo microscope offers the user unprecedented viewing for fluorescence and other advanced applications. Its objectives offer higher numerical apertures (NAs), including a unique 2x objective with an NA of 0.3, producing a resolution of 900 line pairs per millimeter. This objective not only offers much higher resolution for enhanced imaging, it has a correction collar that corrects for up to 5 mm of aqueous media. The collar compensates for the varying refractive indices of water, air, and cellular media when imaging. It is the first such correction collar designed for a stereo microscope. In addition, there is a 1x objective with an NA of 0.15, which is the highest NA for any commercially available stereo objective of this magnification. A comprehensive range of parfocal objectives (0.5x, 1x, 1.6x, and 2x), combined with smooth, trouble-free zooming from 3.5x (using the 0.5x objective) to 230x (using the 2x objective), means the SZX16 user can easily move from whole organism to cellular level and back without complex adjustments. The new near-vertical fluorescence illuminator offers five filter positions and significantly improves signal intensity for extraordinarily bright fluorescence observation even with dimly fluorescing specimens. In addition, the SZX16 offers a variety of features for user-friendly operation. Its high depth of field comes from an enhanced stereo convergence angle that also helps reduce eye fatigue and allows the user to enjoy the benefits of the higher NAs without losing depth of field. The system creates more natural, vivid, and true-to-color images for viewing and documentation. A tilting trinocular head is available for user comfort. The SZX16’s base has been made cooler, lower, and more ergonomic as well. The brightfield mirror rotates 360°, making it easier to work with Zebrafish and similar specimens. The LED base is only 11¼2 inches high, very cool, and lasts up to 13,000 hours. With flicker-free performance, its color temperature is also constant, so no white balance adjustment is necessary. It even allows oblique, DIC-like images to be generated for those who require additional contrast techniques beyond brightfield and darkfield. The SZX10 offers a 10x zoom range, and is available with eight objectives. The SZX10 also features the improved depth of field, enhanced new base, comfortable viewing and many other features of the SZX16. Its bright, true-color, three-dimensional, distortion-free images support both the routine work of identification, comparison, and selection, and also more advanced scientific applications.
Olympus America Inc
(800) 455-8236; www.olympusamerica.com/microscopes


LIS Solution
Scalable and secure
Fletcher-Flora has released encaLaber™, a scalable and secure Web-based laboratory information system (LIS) solution for any size hospital, reference laboratory, or large group practice. encaLaber™ runs on multiple ODBC-compliant databases, in either LINUX or Windows® operating system environments, and allows customers to configure a system that best fits their needs and requirements. Fletcher-Flora even provides flexible pricing options to reduce upfront costs and budget constraints that make it difficult to replace antiquated systems. Its Web-based design provides integrated outreach and real-time availability of results to physicians. In addition, encaLaber comes standard with connectivity middleware that facilitates the integration of third-party clinical systems and communication between the main lab and instruments and devices in remote locations. Rules-based technology helps users improve lab efficiency while safeguarding patient health and privacy.
Fletcher-Flora Health Care Systems Inc
(800) 777-1741; www.fletcher-flora.com


Benchtop Centrifuge
Purges trapped air and bubbles
The new EFD® ProcessMate™ 5000 Centrifuge provides a fast, simple, and cost-efficient way to purge medium-viscosity fluids of bubbles and air pockets that can affect shot-to-shot consistency in critical fluid-dispensing applications. The compact benchtop unit can purge up to four 3-cc, 5-cc, 10-cc, or 30-cc syringes at one time. The on-off switch, timer, and tachometer make operation simple and efficient. Safety features include a locking lid and an electric brake that stops the rotor when the unit is powered down or the lid is opened.
EFD
(800) 556-3484; www.efd-inc.com


Single-Tab Aluminum Foils
For PCR and storage
Excel Scientific has introduced its new AlumaSeal 96™ and AlumaSeal 384™ Aluminum Foils. These sealing foils are classic single-tab-design adhesive sealing foils for protecting samples in microplates during PCR gene amplification or cold storage. AlumaSeal 96 foils are designed to fit easily inside the rim of raised-rim plates. Both foils and their adhesives are heat-resistant and cold-resistant, and are recommended for temperatures from -80°C to +150°C. They are certified to be free of DNase, RNase, and nucleic acid. Both are easily pierceable by pipette tips or robotic probes for sample recovery after processing or storage.
Excel Scientific Inc
(760) 249-6371; www.excelscientific.com


Electrostatic Voltmeter
With millivolt resolution
Trek Inc has introduced Model 325 Electrostatic Voltmeter, an ultrasensitive instrument that is ideal for noncontacting electrostatic voltage measurement and monitoring in applications within high-tech, semiconductor, materials processing, materials science, and R&D sectors. The instrument was specifically designed to be used in applications that require highly accurate, low noise, noncontacting measurement of electrostatic voltages from mVs to +/-40 V over a wide range of probe-to-surface distances. In high-tech manufacturing, applications include electrostatic monitoring of devices sensitive to electrostatic discharge (ESD), and testing of the reliability and characteristics of dielectric materials and films in electronic applications. In semiconductors, Model 325 is designed to measure the surface potential of bare or processed wafers to analyze doping and thin film characteristics. This new electrostatic voltmeter is also useful for measurements of polarization, residual charge, and characterization of electrostatic chucks. In processing, Model 325 can monitor electrostatic charge where the buildup of such charge can cause productivity or yield problems, as in high-end processing of paper, plastic, textile, or other film products. In materials science and R&D, applications include contact potential (surface work function) determination, materials evaluation, and electret studies. Features of Model 325 include sensitivity of 1 mV, speed of response less than 3 ms, and accuracy better than 0.05% of full scale. Trek’s patented low-impedance probe sensor ensures measurement accuracy that is essentially independent of probe-to-test-surface spacing while eliminating the external environmental effects of high humidity and contamination on measurement accuracy. Contaminants include airborne dust, ions, chemicals, and other particulates. The Model 325 Electrostatic Voltmeter offers a higher performance alternative to the company’s Model 320C Electrostatic Voltmeter. While Model 320C measures to a higher voltage range (+/- 100 V), Model 325 offers faster speed of response, lower noise, and higher accuracy. The new model’s smaller probe also increases the unit’s utility in space-constrained environments. The Model 325 was designed to address the ever-more-demanding semiconductor parameters for permittivity, oxide thickness, and integrity, contact potentials, and higher-speed automated voltage profile scanning. Special features of the Model 325 allow the unit’s performance to be tuned to compensate for specific test conditions. Model 325 can be operated as a benchtop unit or in a standard rack (with optional hardware).
Trek Inc
(585) 798-3140; www.trekinc.com


Supermagnetic Beads
For immunotherapy research
Dynal, now part of Invitrogen Corp, has released a new research tool in its immunotherapy range—Dynabeads® ClinExVivo™ CD3/CD28. Using this cutting-edge technology, researchers can isolate and collect T cells from immuno-compromised patients for ex vivo stimulation and expansion in a sterile environment. In the United States, Dynabeads ClinExVivo CD3/CD28 are available for clinical applications only under an approved IND application. Dynabeads ClinExVivo CD3/CD28 superparamagnetic beads are designed with an optimized surface covered with primary CD3 and costimulatory CD28 antibodies. Following a short ex vivo incubation with the patient’s sample, the beads bind with the T cells. The beads and bound T cells are separated from the rest of the sample using the special Dynal ClinExVivo™ MPC® magnet. Researchers then stimulate and expand the T cells ex vivo with Dynabeads ClinExVivo CD3/CD28 in a sterile environment prior to reintroduction to the patient. Boosted T cells, if reinfused, have the potential to strengthen the individual’s immune system to fight diseases, including cancer and HIV. This technology has further potential in autoimmune diseases as well as in gene and stem-cell applications.
Invitrogen Corp
(760) 603-7200; www.invitrogen.com/dynal


Human Tumor Western Blots
Prepared with total protein extracts from normal and tumor tissues
Users may compare normal-tissue proteins with tumor-tissue proteins quickly and easily with Tumor set I and Tumor set II from G-Biosciences. Prepared with total protein extracts from normal and tumor tissues, Tumor set I (TB56-I) includes the uterus, breast, cervix, ovary, testis, prostate, and rectum; and Tumor set II (TB56-II) includes the liver, lung, pancreas, stomach, thyroid, laryngopharynx, and skin.
G-Biosciences
(314) 991-6034; www.gbiosciences.com


Ultralow-Pressure Documenting Calibrator
Designed for processes in critical environments
Setra Systems has introduced the new Micro-Cal Model 869, ultralow-pressure documenting calibrator. The new calibrator has been specifically designed for air-handling processes in critical environments that require portable, high-accuracy and low-pressure documenting calibration to certify pressure needs. The Model 869 easily provides this capability by performing calibration checks on sensors with accuracies as high as .00025 in WC. Traditional laboratory benchtop calibration units are only accurate to .0004 in WC, and require at least 1 full hour to run calibration checks on one unit. To correctly perform on-site tests, many of these basic units need multiple components, such as pressure indicators and generators, voltage and current meters, and data loggers. The new Micro-Cal was engineered to be portable, lightweight, and compact for use in cramped or remote locations. This battery-powered unit provides a minimum of 8 hours of operation, while giving a pressure-reading accuracy close to .0001 in WC; with fast, stable, and repeatable pressure generation better than .0003 in WC. With recorded calibration times as fast as 5 minutes per unit, users will enjoy time-saving benefits as well as substantial cost savings for service and installation time. Setra will also introduce the Model 269, Very Low Differential Pressure Transducer, designed specifically for pharmaceutical environments, with a standard accuracy of ±0.15% FS for better resolution in critical environments. The unit is offered in Base Mount or DIN Rail versions, minimizing installation time with its easy-to-access pressure ports and electrical connections. Additional features include a removable process head, which increases ease of use by eliminating the need to cut tubes, and a detachable terminal block, so field wiring can remain in-situ during calibration. The Model 269 is calibration-secure, requiring a calibration key for making zero and span adjustments.
Setra Systems Inc
(800) 257-3872; www.setra.com


RNA Purification Solutions
Uses animal tissues and cells
QIAGEN has extended its range of RNA purification solutions with miRNeasy kits. These new kits facilitate miRNA research by enabling purification of total RNA, including miRNA or enrichment of miRNA and other small RNAs in a separate fraction. The miRNeasy Mini Kit is suitable for low-throughput purification. The miRNeasy 96 Kit is the first kit available for high-throughput purification in a 96-well format. miRNeasy kits enable purification of total RNA including RNA from 18 nucleotides upward. Alternatively, an miRNA-enriched fraction and a total RNA (>200 nucleotides) fraction can be purified separately. RNA can be purified from a wide range of animal tissues and cells, including difficult-to-lyse tissues such as skin, muscle, and fat. The simple and flexible miRNeasy procedures provide high-quality miRNA suitable for all downstream applications, including quantitative RT-PCR, northern blotting, and microarray analysis. RNA is highly pure, and use of miRNeasy Kits eliminates the possibility of contamination with salts or phenol, which could otherwise interfere with downstream analyses.
QIAGEN
(800) 426-8157; www.qiagen.com/miRNA


A Range of Controls
For use in a QC program
Developed with customer feedback, ControLine solutions continue Advanced Instruments’ commitment to quality and excellence. The controls are designed for use in a QC program to comply with CLIA 1988 for establishment and verification of method performance specs and reportable ranges. The company’s protein-based control kit, ProtinolR, comes in nine 3-mL vials, formulated to three levels: 240, 280, and 320 mOsm/kg H2O, +/- 7mOsm. The urine osmolality control kit, RenolT, comes in nine 3-mL vials, formulated to two levels: 300, and 800 mOsm/kg H2O, +/-10 mOsm. The osmolality linearity set comes in 10 5-mL vials, formulated to five levels: 100, 500, 900, 1,500, and 2,000 mOsm/kg, 0-400 +/-2 mOsm / >400–2,000 +/- 0.5%. All are safe and composed of nonbiohazardous components.
Advanced Instruments Inc
(800) 225-4034; www.aicompanies.com


Antifluorescein- and Antibiotin-Detection Conjugates
To be used for nucleic acid labeling
KREATECH Biotechnology BV has launched enzyme and dye-labeled antifluorescein- and antibiotin-detection conjugates, including SA-PE (Streptavidin R-Phycoerythrin). These conjugates can be used in combination with the company’s PlatinumBright kits for nucleic acid labeling for life science research applications. The PlatinumBright nucleic acid labeling kits, based on the proprietary ULSTM technology, offer the researcher the ability to nonenzymatically label target nucleic acid with a choice of commonly used fluorescent dyes, including fluorescein or biotin, and then proceed to use this labeled material in different hybridization applications. The addition of conjugates that detect biotin and fluorescein will enable researchers to visualize the biotin labeled nucleic acid and amplify the signal of fluorescein-labeled low abundant targets. KREATECH’s ULS technology relies on the special binding properties of transition metals, especially platinum, to form coordinative bonds with biomolecules by binding to specific sites on DNA, RNA, and proteins. In this way, ULS acts as relatively simple “molecular glue” for DNA, RNA, and proteins. As a result of its versatility, customers have a choice of the molecular label attached to the ULS they can use to label the biomolecules of interest. KREATECH also commercializes labeling kits for aRNA labeling, miRNA labeling, small RNA labeling, arrayCGH labeling, general nucleic acid labeling, and protein labeling.
KREATECH Biotechnology BV
+31 20 691 91 81; www.kreatech.com


Homocysteine Reagent Kit
Automated reagent for clinical chemistry analyzers
Equal has introduced a new automated homocysteine reagent kit that is easy to use and set up on most clinical chemistry analyzers. Within the last year, testing for homocysteine has increased 400%. It is now the fastest-emerging test for coronary heart disease risk factors. Homocysteine, an amino acid, is produced as the body metabolizes protein. At high levels, it may damage arterial vessels and raise the risk of cardiovascular disease. Studies have shown that increased plasma total homocysteine levels led to increased risk of vascular disease similar to that of smoking or hyperlipidemia. The ready-to-use kit requires no reagent or sample pretreatment and offers two-point calibration and a low per-test cost. It can be run with other lipid tests, and it also provides 30-day on-board stability.
Equal Diagnostics
(800) 999-6578; www.equaldiagnostics.com


Lab-Data Management Software
Boosts patient-records storage capacity
Beckman Coulter Inc has introduced DL2000 Data Manager v6.5, the latest release of the company’s clinical laboratory instrument software. DL2000 v6.5, when paired with an optional database server, delivers a significantly increased real-time data-storage capability—about 20 times larger—to archive up to 500,000 patient-sample records. With hematology graphics, the database stores up to 300,000 records. This storage size enables larger labs to archive more results for instant recall and comparison. The new v6.5 also offers a hematology slide bar-code scanning capability for labs with a client-review station. With this new function and an optional handheld scanner, the patient-sample bar code can be scanned right at the manual differential station, for error reduction and faster recall. Beckman Coulter’s DL2000 Data Manager connects multiple lab instruments with the LIS, streamlining workflow processes and reducing turnaround time. It manages samples, workflow, and results data from a single workstation, to improve access to test information and pinpoint critical requests and findings. The flexible system eliminates patient ID errors and processing delays with efficient sample tracking and user-defined criteria for auto-validation. Each DL2000 workstation can manage up to three Beckman Coulter instruments simultaneously. As many as five workstations can be networked to manage an entire lab. With automated notifications, the system enables the technologist to focus only on critical tests and samples that need attention, delivering timely information that ensures informed treatment decisions for better patient care. Additional enhancements include new user-definable filter tabs and new instrument and host interfaces. An improved dilution process eliminates mishandling of samples.
Beckman Coulter Inc
(800) 526-3821; www.beckmancoulter.com


Human Genomic DNA Reference Controls for CYP2D6 Gene
Now available for research use
Human Genomic DNA Reference Controls for the Cytochrome P450 2D6 gene (CYP2D6) are now available from Gentris Corp. These controls are isolated from cells collected from individual donors using a proprietary process. All sequences were verified by bidirectional sequencing. Because this method does not introduce artificial DNA sequences into cell lines, the human genomic DNA reference controls most closely mimic the behavior of genomic DNA isolated from human samples. The same genomic sequence will be available each time a control is used, thereby avoiding consistency, consent, and supply issues brought about by the practice of using leftover samples. Each vial contains 10 µL at a concentration of 50 ng per µL. Human Genomic DNA Reference Controls are available for research use only.
Gentris Corp
(866) PGx-9700; www.gentris.com


Enhanced Finnpipette
Featuring ergonomy, flexibility, and safety for large-volume pipetting
Thermo Electron Corp has introduced the enhanced Finnpipette® BioMate plus pipetting aid. The increased motor power allows faster pipetting of volumes from 1 to 100 mL, with batteries that last up to 8 hours under constant use. Comfort and grip are ensured by the lightweight and ergonomic design, which features a new oval-shaped handle for greater “fit” in the palm. Easy, soft-touch controls and the improved “slide switch” give the user totally precise flow control. These make the Finnpipette BioMate plus an excellent choice for all liquid-handling requirements across the pharmabiotech, academic, chemical, environmental, and clinical sectors. The Finnpipette BioMate plus can be fitted with all standard plastic and glass pipettes; and when not in use, the stand supports the Finnpipette BioMate plus and fitted pipette in multiple positions. With easy selection of the aspiration and dispensing speeds via the slide switch, both small and large volumes can be handled with greater speed and precision. This fine control is coupled with a powerful motor that can fill even large pipettes very quickly and a blow-out function that ensures 100% of the contents are dispensed. The BioMate plus is designed with user comfort and safety as a priority. The oval handle fits to the contours of the hand for a secure grip with both the slide switch and valve control within easy reach; and the soft-touch, motorized control minimizes any risk of repetitive strain injury. Furthermore, an exchangeable, in-line PTFE filter provides protection against toxic or corrosive fumes and substances.
Thermo Electron Corp
(508) 482-7000; www.thermo.com


Microscope with Camera
With wide-field eyepieces and a forward-facing noseface
The new Revelation III Microscope, combined with the MiniVID camera, delivers quality imaging at an affordable price that is ideal for use in physicians’ offices or medical schools. The microscope includes 10x/18 wide-field eyepieces and a quadruple forward-facing nosepiece. The optics, DIN Achromatic or Semi-Plan, with 4X, 10X, 40X and 100X oil objectives, provide affordable quality. The microscope also comes with a lifetime warranty on materials and workmanship. The MiniVID camera has an option of either the USB connection option for a computer or RCA output for the television and VCR to fulfill both training and occupational needs. The camera attaches to any standard eyepiece tube and provides imaging.
LW Scientific Inc
(800) 726-7345; www.lwscientific.com


Fluid-Handling Pumps
For diagnostic and laboratory applications
Watson-Marlow Bredel has launched its new, improved 400F/D-series peristaltic pumps, ideally suited for meeting the demanding fluid-handling needs of the OEM industry. This new 400F/D-series of pumps can be delivered for either two or three channels, with individual spring-loaded tracks delivering the highest accuracy and performance flexibility. The 400F/D is an inherent metering pump with repeatability up to 99.5%. These pumps will perform any dosing, metering, or evacuation duties. Watson-Marlow Bredel’s 400F/D-series provides increased application flexibility through an adjustable occlusion, allowing the operator to adjust the track so that the pump will deliver the required pressure. The tracks are also spring-loaded to optimize tube life. The pumps can be delivered with preset occlusion from the factory, according to the customer’s specifications. Another benefit of the individual tracks is the reduced stress on the rotor and gearbox. These pumps have no internal universal joints, valves, dead corners, or glands to impede flow, and the pumps are reversible for back-flushing lines. They can also run dry indefinitely without damage and provide up to a 30’ suction lift.
Watson-Marlow Bredel Pumps Inc
(800) 282-8823; www.watson-marlow.com


Complete Reagent Package
For the ATAC®8000 Random Access Chemistry System
This reagent package includes liquid-stable reagents and calibrators and controls with values for the ATAC System. The company offers a complimentary quality-assurance program for the analyzer, as well as instrument applications and technical support for the use of Pointe Scientific products on the ATAC.
Pointe Scientific
(734) 487-8300; www.pointescientific.com


EGFR-Mutation Test Kit
Creates scope for blood-based prediction of drug response in lung cancer
The DxS EGFR Mutation Test Kit is a molecular assay combining ARMS (allele specific PCR) and Scorpions™, a rapid fluorescent signaling system. In addition to heralding the introduction of blood-based mutation detection, a recently published paper also concluded that patients who were EGFR-mutation positive appeared to have better outcomes with Gefitinib treatment in terms of progression-free survival, overall survival, and response, than those patients who were EGFR-mutation negative.
DxS
+44 (0) 161 606 7201; www.dxsgenotyping.com


Blood-Coagulation Testing System
For managing patients treated with oral anticoagulants
International Technidyne Corp has introduced a new version of its ProTime® Microcoagulation System for use in the management of patients treated with oral anticoagulants. The instrument is designed to be used by both health care professionals and for patient self-testing. The new ProTime system has several new instrument and software features designed to enhance user ease and convenience, increase results-reporting efficiency, improve safety, and reduce transcription errors. The software has been updated to include the ability to auto-send results to a printer or computer quickly and easily. Results can also be transmitted to a laboratory information system or electronic medical record database through a clinical interface. The new ProTime also accepts and stores patient and/or operator ID for reduced transcription errors. Further, the off-meter sampling feature provides unparalleled safety against possible sample contamination and disease transmission. Key design enhancements include an easy-to-read back-lit display and an operator-rechargeable and operator-replaceable battery. ProTime is the only system offering the flexibility of both onboard and optional external quality controls to assure patients and health care professionals that the system is working properly.
ITC
(800) 631-5945; www.itcmed.com


Vials and Accessories
For subzero temperature ranges
Vangard Cryos™ offer a broad line of cryogenic vials and accessories. Cryos cryogenic storage vials are a perfect and comprehensive solution for safe and convenient storage of samples and specimens at a variety of sub-zero temperature ranges. These vials are available from 1-cc to 5-cc capacity; in round-bottom, conical, or self-standing styles. All the vials are packaged sterile with a choice of internal or external screw caps, with silicone gaskets or liners to provide a secure, safe seal. Write-On-Areas and printed volumes along with color Capcodes™ make for quick identification and sample organization. These vials can withstand temperatures to -196°C and can be used in the liquid nitrogen phase when used with properly applied Cryoshrink™ Tubing.
Biohit Inc
(800) 922-0784; www.biohit.com


Ecstasy Test
Available on multiple testing systems
Dade Behring Inc has launched an automated Ecstasy test on its Dimension® chemistry systems. The new test uses the Syva gold standard EMIT® technology. Dade Behring now offers an Ecstasy test on the Dimension chemistry systems and V-Twin®, Viva-E™ and Viva-Jr™ drug-testing systems. The Substance Abuse and Mental Health Services Administration has proposed guidelines specific to mandatory screening for Ecstasy as part of a drug-free workplace program. These new proposed guidelines have led to an increased demand for the Ecstasy test.
Dade Behring Inc
(847) 267-5300; www.dadebehring.com


DP71 Camera
Offers fast display rate, high sensitivity, and low noise
The Olympus DP71 microscope digital camera combines versatility, exceptional color fidelity and ultrafast display and transfer rates, providing unmatched performance in its class for both research and clinical applications. The DP71 is a 12.5-megapixel, 12-bit digital color camera that displays the native CCD’s full-resolution live image at 15 frames per second, a new standard among cameras in its category. It can capture a 12.5-megapixel image with outstanding color fidelity, clarity, and an abundance of detail in less than 3 seconds. In addition, it has numerous resolution options, allowing the user to match its resolution to the microscope objective being used, thereby optimizing the imaging protocol to suit the requirements of the specimen being photographed. The camera provides brilliant color reproduction, making it ideal for pathologists, who require the best possible color fidelity for diagnostic purposes. It also is an excellent choice for fluorescence imaging when signals are weak, thanks to its choice of high-sensitivity, low-noise features: two binning modes, a new custom grayscale algorithm, a special super fluorescence auto-exposure mode, and Peltier cooling (10°C below ambient). An optional removable IR filter model is available for extended imaging into the near-infrared range. With its high-sensitivity, 2¼3-inch, 1.45-million-pixel CCD and piezoelectric motor, the DP71 provides fast performance. Pixel-shifting technology is used to increase spatial resolution from 1.45 to 12.5 million pixels. In live mode, full-frame images (1360 x 1024) are produced at 15 fps for viewing, consultation, or documentation. In addition, the camera has two ultrahigh-resolution modes (4080 x 3072 and 2040 x 1536), and a 680 x 512 mode. To work at high resolutions and save file space, a region of interest function allows the acquisition of smaller areas of the field of view. The camera comes with a short, half-sized PCI interface card that occupies only one slot, allowing the use of additional plug-ins. The software, which can also be used to operate Olympus motorized microscopes, features both standard and custom grayscale functions with up to a 10-fold reduction in exposure time on the custom grayscale option. The Preview Image Quality mode is highly improved for long exposures. The software is intuitive and helps streamline workflow with a customizable toolbar for enhanced control over image acquisition and management. The DP71 features a standard C-mount for attachment to most microscopes, and an elegant new black matte casing with a sleek platinum stripe.
Olympus America Inc
(800) 455-8236; www.olympusamerica.com/microscopes


Hematology Instrument
Uses all-optical laser technology
The newest member of the CELL-DYN family, CELL-DYN Ruby, uses an all-optical laser technology to bring greater efficiency to laboratories by identifying abnormal cells and interfering substances, so more reportable results are obtained on the first review. A midvolume analyzer designed for processing normal to moderately complex patient samples, CELL-DYN Ruby best meets the needs of small- to medium-sized hospitals or large clinics. This analyzer can also serve as a backup to the CELL-DYN Sapphire.
Abbott Diagnostics
(800) 323-9100; www.abbottdiagnostics.com


Slide Labels
Featuring technology to facilitate bar coding of specimen slides
General Data has introduced improvements to its StainerShield labels for tissue and specimen slides. The enhanced StainerShield labels now feature an advanced stain- and solvent-resistant polymeric technology that was developed specifically for laboratory applications. It delivers improved resistance to an increasing number of lab protocols, including exposure to the harshest chemicals, solvents, and stains. StainerShield labels are a part of General Data’s StainerShield family of products and technologies designed for effective bar code-based identification and tracking of tissue cassettes and specimen slides in medical and research labs. Lab technicians print StainerShield labels with patient- and case-specific data in text and bar code format at the individual cutting workstations. The StainerShield labels are then applied to the specimen slides as they are produced, before the slides are exposed to the lab’s staining process. As a result, the specimen slide has a permanent bar code identifier that can be used to positively identify and track the slide through staining, checkout to the pathologist for review, and back to the lab for archiving.
General Data
(800) 733-5252; www.stainershield.com


Automated Imaging Systems
For high-content cellular analysis
The BD Pathway™ 435 is a compact, automated benchtop system that rapidly images cells and tissues in multiwell plates or on microscope slides. A newly designed laser-based auto focus significantly increases image-acquisition speed and overall plate throughput. The system incorporates flexible computer-controlled excitation and emission filters; spinning-disk confocal optics for reduced fluorescence background and 3D imaging; and a long-life, user-friendly metal halide lamp. With updated image-analysis software featuring new tools and wizard-style applications, the BD Pathway 435 confocal bioimager simplifies the process of high-content cellular analysis. The system enables a broad array of fluorescence-based biological applications such as neurite-outgrowth analysis, angiogenesis, protein translocation, colocalization, cell cycle, and 3D cellular exploration. The BD Pathway 435 is ideal for researchers who need high-speed, high-resolution confocal imaging capabilities coupled with powerful and flexible image analysis. For applications not requiring confocal, the BD Pathway 415 is a cost-efficient alternative to the BD Pathway 435. And the system can be field-upgraded to confocal later if applications require it. The introduction of these new imagers complements the recently updated BD Pathway 855 (formerly BD Pathway and Pathway HT) system, which provides versatile live-cell imaging capabilities, including environmental control, liquid handling, and advanced kinetic-analysis software.
BD Biosciences
(800) 245-2614; www.bdbiosciences.com


Specimen Container
Portable units maintain temperature
Duramark now carries a full line of mobile units that can keep laboratory specimens frozen, refrigerated, incubated, or at room temperature. These portable units can be used in a 12-V DC vehicle plug or a standard office power plug (110 V AC). Special battery-saving circuitry ensures that the unit will not drain the vehicle’s battery. Various sizes are available from smaller 18-quart units (18 x 12 x 16 inches) to very large 110-quart sizes (31 x 20 x 22 inches). Additional options are available, including insulated covers, visible temperature alarm units, and temperature data loggers. These durable units are designed for convenience and cost savings.
Duramark Inc
(714) 828-2800; www.duramark.com


Specimen-Tracking Solution
Provides real-time tracking and courier optimization
Duramark has partnered with inCode Wireless (formerly Peak Technologies) to provide a complete solution for specimen tracking and courier optimization to laboratories, hospitals, and medical centers. By using state-of-the-art handheld and stationary computer devices, couriers and the specimens they transport can be identified, tracked, and coordinated. This system will provide real-time specimen tracking/proof of services, effective vehicle monitoring, driver communication, and routing. Additionally, the system comes with a “help” feature. These items will improve turnaround times by accurately tracking materials moving throughout the laboratory/courier network; lower costs by reducing time, expenses, and errors associated with manual or paper-based processes; and enhance customer service by responding quickly to proof-of-service requests.
Duramark Inc
(714) 828-2800; www.duramark.com


Peristaltic Pumps
For sanitary processing applications
Watson-Marlow Bredel has introduced its 620/520 family of peristaltic pumps, which are designed for the accurate metering, dosing, and transferring of corrosive or sensitive fluids in sanitary environments. The 620/520 pumps are ideal for filtration, fermentation, and dispensing applications; and they meet full quality testing standards, including USP class VI, ISO 10993, and USDA requirements. The 620 series introduces market-leading flow rates at pump-head speeds that do not compromise tube life. With their extended performance, 620-series pumps can deliver 50% more flow than the previous model; a single 620RE pump head is capable of 18 L/min and pressures up to 60 psi. This new series provides unrivaled performance with a control ratio of 2650:1. With no valves or seals to clog, the 620-series pumps require minimal maintenance, resulting in reduced downtime, and provide a cost-efficient alternative to other pump technologies. For ultimate processing flexibility and increased flow rates, Watson-Marlow Bredel’s 520-series pumps provide low-shear, contamination-free pumping, and predictable pump service intervals extending validation periods. The 520’s high-powered, brushless DC motor gives it controllability from 0.1 rpm to 220 rpm with speed accuracy to 0.1%. It provides precision dosing and metering, resulting in exceptional batch consistency with an 875,000:1 flow range. The new 520 pump head accepts eight different tubing materials and sizes up to 9.6 mm for flow rates ranging from 4 µL/min up to 3.5 L/min at 30 psi.
Watson-Marlow Bredel
(800) 282-8823; www.watson-marlow.com


Upright Compound Microscopes
For high-quality photomicroscopy
The BC series of upright compound microscopes have modern frames that provide enhanced stability for high-quality photomicroscopy. The ergonomic single-hand focus and stage controls increase workflow while minimizing fatigue. The Kohler Illumination features a field diaphragm and a 20-W, 6-V halogen bulb with an electronic dimmer. The BC series offers binocular and trinocular models with brightfield plan, phase plan, phase achromatic, and infinity optics. Four objectives: (4x, 10x, 40x R, and 100X R [oil]) and two 10x-wide field eyepieces are included. Other objectives and eyepieces are available. The large mechanical stage (209 mm x 140 mm) facilitates specimen handling. The robust all-metal gear-train mechanism is designed to endure years of usage.
Jenco International Inc
(503) 654-9292; www.jencointernational.com


Temperature-Data Logging Devices
With a wide variety of uses
Duramark has expanded its product line to include a wide range of temperature-data logging devices and software through Marathon Products. These units can be used in shipping containers, lock boxes, courier totes, and test kits; and in stationary units such as long-term specimen, chemical, and reagent storage areas. The new micro-DL unit is small and durable, yet it allows for a full range of displaying and recording temperatures. Alarm conditions can be programmed for start or delay, high or low, continuous, or cumulative time settings over alarm conditions. Temperature versus time graphs and charting are also available. The latest technology offering allows for wireless transmission of temperature data. This includes off-site notification via e-mail to PC or cell phone should temperatures exceed user-defined limits.
Duramark Inc
(714) 828-2800; www.duramark.com