This recently introduced liquid Glyca Direct Hemoglobin A1c assay can provide clinicians with a patient’s glycemic history of the previous 90 days.
The Hgb A1c assay has been shown to predict the risk for development of many of the chronic complications in diabetes. This method maintains a certification of traceability to the DCCT reference method.
The three-reagent system quantitatively analyzes glycated hemoglobin and requires the measurement of Total Hemoglobin as well as the Hemoglobin A1c fraction.
The assay first determines the Total Hemoglobin concentration by a single reagent colormetric alkaline hematin method. The measurement of specific Hgb A1c is then performed by a two-reagent latex agglutination inhibition assay. These are performed simultaneously in a chemistry analyzer. The method has a clinically useful analytical range of 1.8 – 17.2% and demonstrates excellent correlation to the HPLC reference method (r=0.97)
Keyword: hemoglobin, A1c