The VANC assay is for the quantitative determination of vancomycin concentration in human serum and plasma. This assay expands the therapeutic drug monitoring (TDM capability of the Synchron LX and CX family of clinical chemistry analyzers.
VANC uses a particle enhanced turbidimetric inhibition immunoassay testing method. It is available in a liquid, ready-to-use, bar-coded reagent cartridge, which eliminates the need for laboratory staff members to mix, hydrate or dilute the reagent before testing.
On Synchron CX systems, the analytical range of the test is between 3.5 and 5 ug/mL. On the Synchron LX systems, the analytical range is from 3.5 up to 60 ug/mL. Within-lot calibration stability is 42 days.
Vancomycin is an antibiotic used in the treatment of serious infections caused by various bacteria. The antibiotic is used intravenously before surgery as a precautionary measure against serious systemic infections. It is also used in patients who are allergic to penicillin and who have heart valve disease or prosthetic heart valves. Vancomycin is one of the most requested TDM assays in the United States.