The Isolute PLD+ protein and phospholipid removal plates from Biotage, Charlotte, NC, provide sample clean-up for blood-based matrix samples for LC-MS/MS analysis. Using a solvent crash/filter process, the plates incorporate a phospholipid scavenging sorbent layer, which removes phospholipids from the sample during the filtration step. Isolute PLD+ plates remove more than 99% of plasma proteins and phospholipids, leading to cleaner extracts and increased sensitivity for a broad range of analytes. Plates can be processed using 96-well compatible positive pressure manifolds, vacuum manifolds, and most automated liquid handling systems. Typical sample volumes of 100 to 200 µL can be processed. For more information, visit Biotage.
Protein Removal Plates Offer Increased Sensitivity for LC-MS/MS Analysis
