Summary: Hardy Diagnostics unveiled a chromogenic biplate designed to help detect and identify carbapenem-resistant Enterobacterales (CRE) and extended-spectrum beta-lactamase (ESBL) producing bacteria.
Takeaways:
- Dual Detection: The HardyCHROM CRE/ESBL biplate features two distinct chromogenic media on one plate, enabling simultaneous detection of CRE and ESBL-producing bacteria from stool specimens.
- Visual Identification: The chromogenic reaction produces easily distinguishable colony colors, allowing microbiologists to identify specific bacteria, such as E. coli, Proteus mirabilis, and Klebsiella pneumoniae, with the naked eye.
- Targeted HAI Prevention: By providing a reliable tool for identifying key pathogens responsible for healthcare-associated infections, the biplate supports healthcare facilities in their efforts to enhance patient safety and prevent the spread of these infections.
Hardy Diagnostics announced the release of an FDA-cleared chromogenic biplate for the detection and identification of carbapenem-resistant enterobacterales (CRE) and extended spectrum beta-lactamase (ESBL) in healthcare settings.
Addressing Healthcare-Associated Infections
According to the Centers for Disease Control and Prevention (CDC), healthcare-associated infections (HAI) are a threat to patient safety. Preventing HAIs is a top priority for the CDC and its partners in public health and healthcare organizations.
To help its lab partners detect and diagnose HAIs, Hardy Diagnostics says it continues to create chromogenic culture media including its latest release of the HardyCHROM CRE/ESBL biplate.
About the HardCHROM BiPlate
One side of the plate holds HardyCHROM CRE, while the other holds HardyCHROM ESBL, both of which are intended for microbiology laboratory partners to be able to detect and identify bacteria that are responsible for the spread of HAIs.
HardyCHROM CRE (carbapenem-resistant enterobacterales) is a selective and differential chromogenic agar medium intended for the qualitative and presumptive detection from stool specimens of Escherichia coli (E. coli) that are non-susceptible to carbapenems and KES (Klebsiella aerogenes, Klebsiella oxytoca, Klebsiella pneumonia, Enterobacter cloacae complex, and Serratia marcescens) that are non-susceptible to carbapenems.
HardyCHROM ESBL is a selective and differential chromogenic medium that is intended for the qualitative and presumptive detection from patient stool specimens of Enterobacterales that are potentially non-susceptible to 3rd generation cephalosporins such as ceftazidime and cefpodoxime and extended-spectrum beta-lactamase (ESBL)-producing E. coli, Klebsiella pneumoniae, and Klebsiella oxytoca.
If these bacteria are present, a chromogenic reaction occurs, allowing microbiologists to easily screen for these microorganisms with just the naked eye.
Further reading: Hardy Diagnostics Releases Enrichment Broth for Candida Auris Detection
E. coli will produce pink-to-magenta colonies; Proteus mirabilis will produce yellow or gold colonies, while Klebsiella pneumoniae will produce blue-to-purple colonies with or without a pink halo.
E. coli, is a common and sometimes beneficial bacterium. However, some strains of E. coli can cause illness ranging from diarrhea to hemolytic uremic syndrome, which can lead to kidney failure and even death.
Proteus mirabilis infects the bladder and can quickly cause bladder or kidney stones.
Klebsiella is a type of bacteria normally found in human stool that can cause HAIs. Klebsiella can cause pneumonia, bloodstream infections, wound or surgical site infections, and meningitis.
Featured image: HardyCHROM CRE/ESBL, Chromogenic Medium, BiPlate. Photo: Hardy Diagnostics
