Purigen Biosystems, Inc., a provider of next-generation technologies for extracting and purifying nucleic acids from biological samples, has launched the Ionic Tissue to Pure DNA Kit. The new kit allows users of the Ionic Purification System to extract increased yields of high-quality DNA from fresh frozen tissue samples with a simple, automated workflow.

The Ionic Tissue to Pure DNA Kit consistently provides more than three times higher DNA yields compared to leading column-based kits. It also features a simple, automated workflow that requires only five minutes of hands-on time per sample. The kit works with limited biological samples and ensures that sufficient amounts of nucleic acid are available for all necessary downstream analysis techniques, such as next-generation sequencing and qPCR.

“Unlocking the most information possible from precious and limited samples has been a longstanding and critical challenge for oncology researchers,” says Barney E. Saunders, PhD, CEO of Purigen Biosystems. “We are moving rapidly to address this challenge and the Ionic Tissue to Pure DNA Kit, combined with our existing portfolio of kits for fresh frozen tissue samples, represents a fundamental change in the efficiency of nucleic acid extraction. More abundant and higher-quality nucleic acids allow for superior next-generation sequencing data.”

The Ionic Tissue to Pure DNA Kit utilizes Purigen’s Ionic Purification System, a benchtop instrument that enables the automated extraction of pure and abundant nucleic acids from a wide range of sample types, including cultured or sorted cells and FFPE tissue. These biological samples are gently lysed and loaded into an Ionic Fluidic Chip. The Ionic System uses the company’s innovative isotachophoresis (ITP) technology to apply an electric field to the chip, which isolates the nucleic acids in their natural, native form. Since the nucleic acids are not denatured or dehydrated, nor are they bound and stripped from fixed surfaces, the process minimizes fragmentation and eliminates bead or buffer contamination. 

The Ionic Tissue to Pure DNA Purification Kit consists of six chips and a reagent set with all necessary enzymes and buffers to perform DNA extraction from 48 samples. The kit is available now through Purigen’s direct sales channels. For more information, please visit: Purigen Biosystems.