Miltenyi Biotec, Bergisch Gladbach, Germany, has extended its portfolio with the MacsPlex exosome kit for humans, enabling the characterization of 37 exosome surface markers in a single experiment. The company developed the kit for the automated characterization of exosomes using flow cytometry. The screening approach is based on fluorescent immune conjugates—MacsPlex exosome capture beads—which are included in the kit and bind different exosome-specific epitopes. The MacsPlex exosome detection reagent marks the bound exosomes with the pan-exosome markers CD9, CD63, and CD81. The result is a sandwich complex, consisting of the MacsPlex exosome capture bead, the exosome, and the detection reagent, which can subsequently be analyzed based on their respective fluorescent properties. Using flow cytometry, one can obtain semiquantitative data on 37 exosomal surface epitopes. For more information, visit Miltenyi Biotec.