TwistDx, Cambridge, UK, has launched a line of liquid-format recombinase polymerase amplification (RPA) kits that are suited for rapid testing applications and high-throughput laboratory use. The isothermal DNA/RNA amplification technology represents a versatile solution for nucleic acid detection, offering the same specificity as polymerase chain reaction (PCR) but with results typically available within 3–10 minutes.

The newly available TwistAmp liquid kits are designed to simplify integration of RPA technology into existing laboratory workflows, offering a fast and user-friendly alternative to PCR—potentially using the same primers—without the need for a thermocycler. The liquid format also simplifies the development of miniaturized or custom assay configurations and the creation bulk master mixes, as well as allowing users to vary the ratios of individual assay components to optimize their workflows.

Niall Armes, TwistDx.

Niall Armes, PhD, TwistDx.

“The ever-growing number of peer-reviewed publications using our technology demonstrates the benefits of RPA as a genuine alternative to traditional PCR techniques,” says Niall Armes, PhD, CEO of TwistDx. “The recent launch of our TwistAmp liquid kits represents the next step in the development of this technology, helping scientists across a much broader range of applications—from laboratory diagnostics to environmental testing—to take advantage of the speed and sensitivity our approach offers.”

For more information, visit TwistDx.