NanoMosaic, a provider of nanoneedle technology for proteomics and multiomics, established a scientific advisory board (SAB) to support its vision to bring nanoneedle-powered digital proteomic tools to the diagnostic community, and also announced Abhishek Chatterjee, PhD, professor of chemistry at Boston College, has joined the SAB.

Chatterjee’s lab combines elements of chemical biology, synthetic biology, and virology to develop new strategies for understanding and manipulating biological processes in mammalian cells. Chatterjee has developed various novel genetic code expansion tools to allow site-specific incorporation of enabling noncanonical amino acids into proteins in vivo

“NanoMosaic’s powerful MosaicNeedle technology has the potential to revolutionize the world of protein detection and quantification. With its great sensitivity over an exceptionally broad dynamic range, as well as its high throughput, it has opened the door to endless possibilities in this field,” Chatterjee says. “I am thrilled to join the NanoMosaic SAB and help this talented team to explore the full potential of this groundbreaking technology.”

Chatterjee is also co-founder, senior advisor, and Chair of Scientific Advisory Board of BrickBio Inc.

“We are truly thrilled to have Abhishek on NanoMosaic SAB. His seminal work has led to precise, stable and highly efficient site-control of conjugation that unleashes the most optimal function of diagnostic and therapeutic molecules,” says Qimin Quan, PhD, co-founder, CSO and Chair of SAB of NanoMosaic. “Enabling site-specific conjugation capabilities on the NanoMosaic Tessie platform will bring the performance and consistency of diagnostic assays to the next level.”

In June 2022, NanoMosaic announced partnership with BrickBio to introduce site-specific, stable conjugation to the antibodies for the NanoMosaic CDx neurology panel. The novel antibody has been designed to have higher affinities and enhanced performance on NanoMosaic Tessie platform.

“Abhishek adds significant value to NanoMosaic, as the company embarks on developing next-generation probes, with novel scaffold and capture mechanisms, for nucleic acids and proteins,” says John Boyce, president, CEO, and co-founder of NanoMosaic, as well as co-founder of Tiger Gene, LLC. “These novel capture and interrogation methodologies, that work exclusively with nanoneedles will significantly benefit both the research and diagnostic endeavors of scientists and physicians” Boyce concluded.

Featured image: The NanoMosaic platform, Tessie, alleviates the bottlenecks in proteomics analysis and provides an end-to-end solution that enables first of its kind protein interrogation and multi-omics analysis within a single chip on one run. Photo: NanoMosaic