Naveris, a provider of precision oncology diagnostics for viral-induced cancers, announced the launch of the NAVigate-HPV Registry, an initiative aimed to expand the applications of the company’s circulating Tumor Tissue Modified Viral (TTMV)-HPV DNA blood test

The NavDx test provides a non-invasive and precise method that aids in the detection of HPV-driven cancers before there is clinical or radiographical evidence of disease, the company says. Data supporting the clinical validity and utility of NavDx have been published in nearly 20 peer-reviewed publications.

Real-World Data in the NAVigate-HPV Registry

The NAVigate-HPV Registry aims to enrich the understanding of HPV-driven cancers while fostering a collaborative ecosystem where physicians and patients contribute to the evolution of cancer care.

“The NAVigate-HPV Registry will act as a catalyst for the development of personalized approaches for the treatment and management of patients with HPV-driven cancers,” says Adam Raben, MD, Chair of Radiation Oncology at ChristianaCare and the Helen F. Graham Cancer Center & Research Institute, and a member of the NAVigate-HPV Registry Steering Committee. “By integrating real-world data from across the United States, the registry will unlock additional clinical insights potentially leading to a better understanding of disease behavior, new treatment options, and ultimately improved outcomes for patients.”

A Growing HPV Registry

Participating investigators will include providers who order NavDx in their routine clinical practice. Eligible subjects must have or have had an HPV-driven cancer and have received at least one NavDx test. It is expected that the NAVigate-HPV Registry will encompass more than 1,000 patients within the first year and grow to more than 5,000 patients within five years.

“While the evidence supporting use of the NavDx test in surveillance is unambiguous, the addition of multi-institutional longitudinal data from the NAVigate-HPV Registry will advance our understanding of the test’s pivotal role in diagnosis, therapeutic decision making and overall disease management,” says Catherine Del Vecchio Fitz, PhD, SVP, Medical Affairs and Data Insights at Naveris. “As the leader in precision oncology diagnostics for viral-induced cancers, Naveris is well-positioned to support the creation of this registry. We are thankful to our collaborators who have made this registry a reality, and we look forward to unlocking new possibilities to positively impact patient care.”

Further reading: New Ways to Track HPV-Positive Head, Neck Cancer Recurrence