Roche, Basel, Switzerland, has launched the Discovery 5-Plex procedure and reagents for immunohistochemistry (IHC) research applications. This is the first preoptimized, fully automated multiplex procedure available on the Ventana Discovery Ultra instrument.

Scientists globally are faced with the growing need to extract more information from limited tissue samples. The Discovery 5-Plex procedure allows researchers to investigate up to five biomarkers on a single slide, preserving tissue and maximizing data. The procedure provides researchers with a preoptimized workflow that simplifies the staining process. The ready-to-use detection reagents provide crisp, specific signals and distinct information about protein coexpression patterns.

Ann Costello, Roche Tissue Diagnostics.

Ann Costello, Roche Tissue Diagnostics.

“To better investigate the complexities of cancer biology and possible treatment strategies, it is increasingly important to detect multiple biomarkers on a single slide,” says Ann Costello, head of Roche Tissue Diagnostics. “The launch of the innovative Discovery 5-Plex procedure advances automation in multiplexing technology, which is expected to play a critical role in cancer research in the future.”

As part of the launch, four new fluorescent kits used for the procedure will be commercially available: Discovery FAM kit, Discovery DCC kit, Discovery Red 610 kit, and Discovery Rhodamine 6G kit.

For research use only.

For more information, visit Roche.