productA compilation of current information on obesity and diabetes is now available from Sigma-Aldrich Corp. The brochure reviews the reasons for increases in obesity and diabetes, as well as the mechanisms of energy homeostasis, and the effect of peptides, cytokines, and biogenic amines on food intake. The brochure also reviews the insulin-signaling pathway, the roles of protein tyrosine phosphatases, peroxisome proliferator-activated receptors, and c-Jun N-terminal Kinase (JNK) kinases in diabetes. More than 550 Sigma-Aldrich products are highlighted, including interleukin proteins and antibodies, leptin peptides and antibodies, orexins, neurotrophic factors, and products for lipid-signaling protein phosphorylation and gene regulation.

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