Droplet digital PCR can detect covid-19 cases qPCR misses

By Monica Herrera, MD, and Carolyn Reifsnyder

As of January 4, 2021—nearly a year after the Centers for Disease Control and Prevention (CDC) and Washington state reported the first confirmed case of covid-19 in the United States—the US death toll from the disease had reached more than 351,000 people.1 Public officials can argue what caused such a high case count in this country, but one thing is certain: SARS-CoV-2 infection, like the illness it causes, is hard to detect, trace, and defeat.