Definiens, Carlsbad, Calif, has released the latest version of its image analysis software for quantitative digital pathology. Tissue Studio 4.0 provides greater flexibility, more accurate and consistent results, and the ability to use any chromogen for single- and dual-stain immunohistochemistry (IHC) quantification in research applications.

“Tissue Studio is a comprehensive solution that is easy to use without any prior experience with image analysis or programming, enables customizable, scalable configurations to meet changing needs, and provides significant flexibility for users,” says Thomas Heydler, CEO of Definiens.

By providing morphological fingerprints and biomarker expression profiles on a cell-by-cell basis, the system enables comprehensive and consistent data for any tissue-based assay. Tissue Studio accurately detects regions of interest and distinguishes cell types and cell subtypes within target regions across tissue slides. It also determines morphology and expression profiles according to individual cell or cell compartment.

The system supports applications for single or multiplexed immunohistochemistry, immunofluorescence, and in situ hybridization in the areas of oncology, immunology, angiogenesis, metabolic disorders, toxicology, and others. Features include customizable configurations and add-ons for interactive data review, quality control, and data mining, as well as the ability to create customized image analysis solutions within 20 minutes.

For research use only. For more information, visit Definiens.