Definiens, Carlsbad, Calif, has released Tissue Studio 4.2, an updated tissue analysis software package designed to provide improved image analysis functionality.

The image analysis system for biomarker and morphological profiling was developed to overcome the variability inherent in biological staining. The software seeks to detect regions of interest accurately and distinguish cell types and cell subtypes within target regions across any number of tissue slides.

New benefits available with Tissue Studio 4.2 include a tissue microarray (TMA) brightness slider for improved TMA core detection, minimizing the number of cores that traditionally require manual annotation; improved needle biopsy registration, with automatic alignment for needle biopsies to allow more accurate transfer of the regions of interest between consecutive slides; and “heat maps” that are based on combinations of readouts and object features, allowing a more sophisticated visual review of the local distribution of biomarker expression.

Licenses for previous versions of Definiens products will continue to function. However, current Tissue Studio users can download the new releases by contacting [email protected].

For more information, visit Definiens.