The kit supports both manual and automated workflows to reproducibly isolate high molecular weight DNA suitable for long-read sequencing.
Thermo Fisher Scientific has introduced the Applied Biosystems MagMAX HMW DNA Kit, providing a streamlined manual and automated extraction workflow to enable the reproducible isolation of High Molecular Weight (HMW) DNA suitable for long-read sequencing.
The MagMAX HMW DNA Kit is designed to deliver high-integrity DNA with large, intact fragments from diverse samples using both manual and automated protocols to meet the needs of laboratories with minimal processing time.
Expanding genomic research in industries like biotech and pharma, clinical, and academia has increased the need for a streamlined and efficient option for high-throughput long-read DNA sequencing. According to a news release from the company, until now, researchers have needed different HMW DNA kits depending on sample type and workflow. In addition, manual preparation has led to inconsistent DNA quality and delays in research timelines, according to the company.
“Researchers conducting long-read sequencing can have different sample types, throughput volumes, and workflows, but they also require reliable, efficient, and flexible HMW DNA isolation that fits their evolving demands,” says Kevin Lowitz, vice president and general manager of sample preparation at Thermo Fisher, in a release. “Our HMW DNA Kit simplifies DNA extraction, providing an automated option for a traditionally manual process, reducing bottlenecks and helping researchers use time efficiently. We’re enabling our customers to accelerate their critical research in oncology and genomics.”
DNA Kit Designed to Improve Scalability
The MagMAX HMW DNA Kit delivers HMW DNA with fragment sizes exceeding 100 kb in under two hours, with an average of 20 to 30 minutes of hands-on time. It offers automated workflows compatible with Thermo Scientific KingFisher Duo Prime, Flex, and Apex platforms. A range of protocols and custom product formats, including bulk reagents, are designed to improve scalability and adapt as research demands evolve.
“In our lab, we rely on long-read DNA sequencing to research genomic structure, including variations that could impact our understanding of human disease,” says Alexis Tapanes-Castillo, PhD, associate professor of biology and lab director at St. Thomas University and Galatea Bio Faculty Fellow, in a release. “Thermo Fisher’s new MagMAX HMW DNA Kit has provided our team with quick, simple, and scalable solutions and helps ensure our technology yields high-quality, high molecular weight DNA from our samples.”
Photo caption: Applied Biosystems MagMAX HMW DNA Kit
Photo credit: Thermo Fisher Scientific
