Collaboration will provide plug-and-play protocols for the Chromium Single Cell Platform on SPT Labtech’s firefly liquid handling system.


SPT Labtech and 10x Genomics have announced a strategic partnership to provide automated workflows for single cell research, allowing scientists to scale experiments on 10x’s Chromium Single Cell platform through optimized protocols on SPT Labtech’s firefly liquid handling platform.

The collaboration will provide firefly users with access to ready-to-run methods developed by both companies’ application teams. These protocols are designed to streamline single-cell assay workflows and improve reproducibility, efficiency, and scalability. Future plans include expanding the partnership to include the Visium Spatial platform.

The partnership builds on 10x’s acquisition of Scale Biosciences, which was already partnered with SPT Labtech. Many firefly users currently rely on Scale Biosciences chemistries, and the expanded collaboration will provide researchers access to 10x’s full range of single cell and spatial solutions.

Customer-generated data demonstrating how automated liquid handling streamlines single cell library prep workflows will be presented at the American Society of Human Genetics conference. The development of the methods has been informed by application work conducted in customer labs, with the preparation workflow addressing scalability challenges in single cell transcriptomics.

“Single cell experiments are a critical area of focus for our firefly community. Working closely with 10x Genomics has been key to understanding the specific challenges and needs of researchers in this space,” says Morten Frost, chief commercial officer at SPT Labtech, in a release. “By making these optimized methods available in the firefly cloud, we are empowering scientists with easier access to cutting-edge tools for single cell discovery, while reducing barriers to adoption of advanced workflows.”

The partnership combines the flexibility of firefly automation with 10x’s GEM-X chemistry. “10x Genomics is committed to enabling researchers everywhere to uncover new insights into biology through our single cell solutions,” says Brooke Murphy, vice president of strategic marketing at 10x Genomics, in a release. “This partnership with SPT Labtech will allow more labs to seamlessly automate their workflows, combining the flexibility of firefly automation with the robustness of our GEM-X chemistry, ultimately accelerating breakthroughs in human health.”

Both companies will exhibit at the American Society of Human Genetics annual meeting, Oct 14-18 in Boston, where customer data and new workflows will be highlighted.

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