The collaboration integrates Ultima’s sequencing workflows with Hamilton’s Microlab STAR liquid handling platform to improve lab efficiency and support production-scale sequencing.


Ultima Genomics has partnered with Hamilton to automate sample preparation and amplification workflows for Ultima’s sequencing systems using Hamilton’s Microlab STAR liquid handling platform.

The global agreement involves jointly developing automation scripts for Ultima’s sample preparation and amplification workflows. The collaboration also supports integration with existing library preparation approaches, enabling sample preparation, amplification, and workflow consolidation on an automated platform.

The partnership aims to help laboratories improve operational efficiency, reduce hands-on time, and support production-scale sequencing by combining Ultima’s next-generation sequencing (NGS) technology with Hamilton’s automation capabilities.

“At Ultima Genomics, our goal is to build best-in-class sequencing technology, and through partnerships, provide our customers the ability to choose, and build end-to-end solutions from an open ecosystem of best-in-class technology and applications providers,” says David Peoples, chief business and financial officer, in a release. “This milestone partnership with Hamilton pairs our next generation sequencing solutions with Hamilton’s world-leading automation expertise and will enable customers to seamlessly integrate workflows with Hamilton and Ultima technology.”

Addressing Production-Scale Genomics Bottlenecks

The collaboration aims to address what the companies describe as a critical bottleneck in production-scale genomics by delivering complete workflow automation that supports both research and translational applications.

Hamilton says its automation expertise enables laboratories to adopt scalable NGS workflows with improved efficiency, reproducibility, and user experience. The integration is designed to reduce time spent on manual processes while increasing actionable data generation.

“The modern genomics landscape requires more than just fast sequencing; it demands a seamless transition from raw sample to actionable result,” says Michael Mouradian, vice president of scientific strategy and market development at Hamilton Company, in a release. “Together, we have addressed this market need by coupling Hamilton’s Microlab STAR liquid handling platform with the Ultima sequencing platforms.”

The partnership ensures that Ultima’s high-capacity sequencing technology is supported by automated sample preparation, creating what the companies call an end-to-end production-scale solution.

Supporting Scalable Sequencing Applications

The automation integration is intended to enable Ultima customers to scale their research and accelerate scientific discovery across high-throughput applications. The simplified user experience allows laboratories to push the scale of their operations while maintaining flexibility and performance.

Ultima’s sequencing architecture uses what the company calls “sequencing-on-a-wafer” technology, designed to drive down sequencing costs and scale beyond conventional sequencing technologies. The partnership with Hamilton’s liquid handling platform creates a front-end automation solution matched to this high-capacity output.

The collaboration supports Ultima’s mission to expand access to sequencing at scale while enabling researchers to focus on biological insights rather than technical limitations, according to the companies.

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