Summary: Verichem Laboratories’ new Matrix Plus Chemistry Reference Materials are a comprehensive set of liquid-stable calibrators for chemistry assays on diagnostic instruments, featuring multiple analyte concentrations and designed to enhance system quality control and compliance.

Takeaways:

  1. Versatile Calibration: The Matrix Plus Chemistry Reference Materials offer six concentration levels across seven analytes (BUN, Calcium, Creatinine, Glucose, Magnesium, Phosphorus, Triglyceride), supporting diverse diagnostic systems and methodologies.
  2. Enhanced Accuracy and Stability: With a buffered protein matrix, consistent pH, and liquid stability, these materials reduce matrix variations and reconstitution errors, ensuring reliable calibration and compliance with CLIA mandates.
  3. Comprehensive Documentation: Each product comes with a Certificate of Analysis and is verified against NIST standards, providing detailed testing data and ensuring high-quality performance across multiple analyzers.

Verichem Laboratories unveiled new multi-analyte, multi-level, and completely liquid-stable Matrix Plus Chemistry Reference Materials, designed for the calibration verification of chemistry assays on diagnostic instrument systems. 

These materials, along with the optional stand-alone and ultra-high Level F, comprise a comprehensive set containing six separate concentration levels of seven individual chemistry analyte components. 

The analytes available include Blood Urea Nitrogen (BUN), Calcium, Creatinine, Glucose, Magnesium, Phosphorus, and Triglyceride. These materials not only support overall system QC and CLIA compliance but serve as valuable tools in determining a clinical system’s bias to the known value, with all being suitable for use on multiple analyzers utilizing a wide variety of testing methodologies, including visible spectrum, ultraviolet, kinetic, and/or endpoint.  

About the Matrix Plus Chemistry Reference Materials

All of Verichem’s Matrix Plus Chemistry Reference Materials incorporate a buffered protein-based matrix for serum-like reactivity and are intended to be treated just as patient specimens, as per CLIA mandates. The product formulation displays remarkable optical clarity and is free of glycols, surfactants, azides, and other interfering substances. 

By maintaining a constant protein content, and neutral pH across concentration levels, the unique formulation and CLSI EP06-A set point design of these materials are critical for the independent determination of test method accuracy, sensitivity, linearity, and reportable range. Plus, the use of highly purified source components, and the liquid stable format, eliminates matrix variations and reconstitution errors commonly experienced with lyophilized, or other serum-based products.  Plus, each active component concentration is verified against available Standard Reference Materials from the National Institute of  Standards and  Technology (NIST)  and fully documented with a Certificate of Analysis containing lot-specific testing data. 

Verichem’s Matrix Plus Chemistry Reference Materials are packaged for multi-use and are filled within easy-to-use, opaque polyethylene dropper vials containing an ample 15.0mL fill volume to cover multiple verification testing and troubleshooting events while featuring an exceptional open-vial and product stability claim of 21 months from date of manufacture.