This company has introduced an application for the determination of C-reative protein on the Bayer/Technicon RA systems.
The application uses a CRP reagent formulation that this company says is approximately 50 times more sensitive than traditional CRP reagents.
The reagent is a two-part liquid. Its reaction sequence involves the use of latex particles coated with antibody-specific to human CRP. The particles aggregate in the presence of CRP from the sample forming immune complexes. The immune complexes cause an increase in light scattering, which is proportional to the concentration of CRP in the serum. The light scattering is measured by reading the turbidity (absorbance) at 570 nm.
The assay range for this reagent is 0.010 to 1.000 mg/dl. Precision studies performed on human CRP control serums yielded CVs of 3.52% on a level of 0.14 mg/dl and 1.30% for a level of 0.78 mg/dl. The liquid, stable reagent comes in kits of 1x20ml (R1) and 1x20ml (R2). Calibrators and controls are also available.
Pointe Scientific
www.pointescientific.com
Keyword: reagent, CRP
