The REAADS von Willebrand factor activity ELISA uses a purified monoclonal antibody that recognizes the portion of the vWF molecule that binds platelet glycoprotein Ib. This is the same portion of vWF that is activated by ristocetin in the Ristocetin Cofactor Assay. Ristocetin Cofactor methods are technically demanding and have considerable inter- and intravariability. Also available is a full panel of ELISA format tests for the assessment of vWD, which includes the REAADS vWF activity test, the Corgenix Collagen binding assay (for investigational use only), and the REAADS vWF antigen test.
(800) 729-5661; www.corgenixonline.com