The collaboration combines liquid handling technology with ultra-sensitive transcriptomic workflows to improve throughput and reproducibility.
SPT Labtech and Alithea Genomics have partnered to automate single-cell transcriptomic workflows by integrating Alithea’s MERCURIUS FLASH-seq single-cell RNA-seq protocol with SPT Labtech’s firefly liquid handling platform.
The automated workflow addresses bottlenecks in single-cell transcriptomics research by combining firefly’s low-volume precision dispensing with Alithea Genomics’ scalable RNA-sequencing chemistry. The collaboration aims to improve reproducibility, throughput, and accessibility for single-cell studies as demand grows for higher-throughput, cost-efficient single-cell sequencing.
Single-cell transcriptomics drives advances in cell biology, immunology, and drug discovery, but many workflows remain limited by manual library preparation steps that can introduce variability and constrain throughput. The automated solution is available immediately to customers worldwide through both companies’ application support teams.
“Our mission has always been to make high-throughput and high-quality RNA-seq accessible and scalable for any lab,” says Riccardo Dainese, CEO and co-founder of Alithea Genomics, in a release. “By combining MERCURIUS FLASH-seq and MERCURIUS Total DRUG-seq with SPT Labtech’s firefly, we’re removing key bottlenecks in library preparation workflows. This partnership simplifies complex processes, drives down costs, and empowers researchers to focus on discovery.”
Platform Capabilities
MERCURIUS FLASH-seq offers gene detection sensitivity on ultra-low input samples and single-cells. The integration with firefly’s liquid handling capabilities enables laboratories to achieve consistent results across varied throughput needs, from discovery-scale to large-scale experimental designs.
“This collaboration represents a step toward broader automation of complex RNA workflows, supporting the growing integration of transcriptomics into translational and clinical research,” says Morten Frost, chief commercial officer at SPT Labtech, in a release. “Implementing this workflow on firefly, laboratories can achieve a new level of efficiency, reproducibility, and throughput. The modular architecture of firefly supports both discovery-scale and large-scale experimental designs, enabling consistent results across varied throughput needs.”
The automated workflow addresses the increasing need for standardized single-cell RNA sequencing protocols in both academic and research environments. By automating sensitive RNA-seq protocols, laboratories can reduce manual intervention while maintaining the precision required for single-cell analysis.
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