The expanded unique dual index set enables clinical and research labs to multiplex up to 384 samples on Illumina sequencing platforms while maintaining existing SureSeq workflows.
OGT has expanded its SureSeq Universal NGS Unique Dual Index (UDI) portfolio, enabling clinical and research laboratories to multiplex up to 384 uniquely indexed samples in a single sequencing run, according to a company release.
The expansion quadruples the platform’s indexing capacity from 96 to 384 unique dual indexes, providing high-throughput laboratories with a direct method to scale sample volume while maintaining established workflows, software, and data quality standards, according to OGT.
Scaling High-Throughput Sequencing
As diagnostic and research sequencing volumes increase, laboratories often face batching delays and capacity bottlenecks. According to the company, the expanded 384-index offering is designed to better utilize high-capacity Illumina sequencing platforms, which helps laboratories improve operational efficiency, minimize batching constraints, and lower per-sample run costs.
The new indexes integrate directly into existing SureSeq library preparation protocols and analysis software, eliminating the need for laboratories to redesign workflows or revalidate operational steps, according to OGT.
“As sequencing demand continues to grow, laboratories need practical ways to increase throughput without adding complexity,” says Gareth Thomson, executive vice president of commercial operations at OGT, in a release. “By expanding SureSeq Universal NGS indexing capacity to 384 samples per run, we’re helping laboratories reduce batching constraints and costs per sample to maximize the value of their existing sequencing infrastructure. All the while, customers can still expect the same workflow consistency and performance they rely on from SureSeq.”
OGT stated that the expanded Unique Dual Index set delivers performance equivalent to its existing 1–96 index sets, while supporting confident, multiplexed sequencing through unique dual indexing.
Photo credit: OGT
