This Rabbit anti-c-Met antibody can be used for IHC detection of formalin-fixed paraffin-embedded tissues and Western blotting of human samples.
C-Met is a protooncogene and a cell-surface receptor for hepatocyte growth factor. It has tyrosine kinase activity and consists of alpha and beta subunits linked by a disulfide bond.
C-Met has been associated with progression and metastasis of cancers. It is over-expressed in many cancers and the Met gene is often amplified between tumorigenesis and metastasis. It is a prognostic marker for breast cancer, gastric carcinoma, endometrial carcinoma, and others.
Keyword: cancer, antibody