A new study reported data on a large number of hospitalized moderate-to-severe COVID-19 patients and correlates their serum thyroid hormone levels with illness severity, mortality, and other biomarkers to critical illness.
Among hospitalized patients with COVID-19, an elevation of serum reverse triiodothyronine (rT3) levels was the most frequently observed change (∼63%), followed by high serum elevated free thyroxine (fT4) levels (∼21%) and low serum thyrotropin (TSH) levels (∼7.3%), researchers reported in Thyroid.
The observational, longitudinal, prospective cohort study assessed thyroid hormone levels and their association with serum proinflammatory biomarkers and COVID-19–associated severity and mortality.
A total of 245 patients hospitalized with confirmed COVID-19 infection at a tertiary referral hospital in Brazil from June 2020 to August 2020 were enrolled.
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