The system features advanced thermal technology and modular block configurations to support complex molecular biology protocols.

Thermo Fisher Scientific has launched the Applied Biosystems PowerFlex Thermal Cycler, a next-generation polymerase chain reaction (PCR) instrument designed to improve flexibility and productivity for molecular biology laboratories.

PCR remains a foundational technique in life science research, and laboratories are increasingly sharing instruments across teams while managing more complex workflows. The PowerFlex Thermal Cycler was developed to address these needs through new block technology and precise thermal performance.

“Today’s labs are being asked to run more complex PCR workflows, often across shared instruments and under increasing time pressure. That’s where traditional systems start to fall short,” says Pawan Singh, vice president and general manager, molecular biology, Thermo Fisher Scientific, in a release. “With the PowerFlex Thermal Cycler, we’ve reimagined flexibility and performance together so researchers don’t have to choose between speed, accuracy, and ease of use. We’ve also added support for fully skirted plates to enable lab automation.”

Modular Configurations for Throughput

The system is available in two models to accommodate different laboratory requirements. A standard 96-well configuration offers broad plate compatibility for existing environments. For laboratories running multiple assays, a 3×32-well configuration features independently controlled VeriFlex blocks. This allows three different protocols to run simultaneously on a single instrument, helping to maximize bench space.

The technology is engineered to shorten run times while maintaining the reproducibility required for both routine and complex molecular biology workflows.

“We especially value the flexibility of running three independent experiments simultaneously, as well as the ability to set precise ramp rates in °C per second to optimize our protocols,” says Maria Lung, a research scientist at Xpress Genomics AB, in a release. “The intuitive interface and the option to easily share log files provide additional confidence and support.”

Interface and Automation Support

Operation is managed through a 10.1-inch touchscreen with a user-friendly interface. The system includes built-in simulation capabilities and AI-assisted Smart Help features to guide users through setup and troubleshooting, which the company says helps reduce training time and minimize workflow disruptions.

The PowerFlex Thermal Cycler is intended for use in life science research, biotechnology, pharmaceutical research, food testing, and human identification workflows. The platform is designed to support future expansion as laboratory needs evolve.

The instrument is currently designated for research use only and is not for use in diagnostic procedures. Additional information regarding technical specifications and PCR workflow solutions is available through the company’s digital platforms.

Photo caption: Applied Biosystems PowerFlex Thermal Cycler

Photo credit: Thermo Fisher Scientific

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