The proteinase-3 native auto-antigen from the Binding Site, San Diego, is designed for use as an integral component in solid phase for ELISA-based immunoassay test procedures. Autoantibodies to proteinase–3 are typically found in the sera of patients with active Wegener’s granulomatosis and in other types of systemic vasculitis, including microscopic polyangiitis, idiopathic crescentic glomerulonephritis, Churg-Strauss syndrome, and polyarteritis nodosa. Derived and sourced from human neutrophils, the proteinase–3 native auto-antigen is free of HBs-Ag, HCV, HIV-1, and HIV-2, and exhibits a purity level greater than 95%. This proteinase–3 (cANCA) native auto-antigen is available in two separate convenient and operator-oriented packaging formats including 1.0 mg and 0.2 mg standard fill vials, with bulk packaging configurations also available.  For more information, visit the Binding Site.