The Sm antigen from Binding Site, San Diego, is intended for use as a critical component in solid-phase ELISA-based diagnostic testing procedures. Anti-Sm antibodies have been found in approximately 25% of patients with Systemic Lupus Erythematosus (SLE) and often occur in combination with auto-antibodies to other antigens, including DNA, Histone, RNP, SSA (Ro), and SSB (La). Sourced from bovine thymus muscle, the Sm antigen displays a product purity level greater than 90%, as assessed by SDS gel electrophoresis. The Sm antigen is available in operator-oriented fill formats of 1.0 mg and 0.2 mg and offers extended shelf life and lot-to-lot consistency. For more information, visit Binding Site.