Noviplex cards from Shimadzu Scientific Instruments, Columbia, Md, allow users to collect a volumetric sample of plasma (2.5 or 5.0 µL) from a nonvolumetric application of whole blood within minutes. Between 20 and 75 µL of whole blood from a fingerstick is required to collect a volumetric plasma sample. Noviplex can be used as a single step, solid-phase method for sample preparation and analyte extraction, eliminating the need for solid-phase extraction, centrifugation, and evaporation. The Noviplex card ensures 99% removal of red blood cells and provides plasma sampling volumes of either 2.5 or 5 µL. The tool offers inter-card CV of ~1% in plasma collection volume at constant hematocrit (HCT), and inter-card CV of 2% collection volume variation with 20% to 71% HCT. Proteins are deposited as a monolayer upon drying, while metabolites are present in the protein monolayer. For more information, visit Shimadzu Scientific Instruments.
