The BiOS line of automated storage systems from Hamilton Storage Technologies, Franklin, Mass, is designed for storage of sensitive biological samples at temperatures down to -80°C. Three different configurations are available to ensure the integrity of 100,000 to more than 10 million long-term samples, based on 1.0-mL tubes in 96-position racks. The BiOS M and Bios L offer a compact footprint for medium-sized labs that require moderate to large storage capabilities. The BiOS XL enables storage of millions of samples in dedicated facilities. Self-contained chest freezer compartments climate-controlled to 80°C preserve temperature stability and energy efficiency even in case of emergency. 1D and 2D barcode reading and sample tracking provide complete chain-of-custody documentation, with software tools to support 21 CFR Part 11 compliance. For more information, visit Hamilton Storage Technologies.