Cerilliant introduces two new Certified Spiking Solutions® of 1a, 25-Dihydroxyvitamin D3 and 1a, 25-Dihydroxyvitamin D2, the biologically active forms of vitamin D, to further augment its offering of Snap-N-Spike® reference solutions for vitamin D testing by LC/UV or LC-MS/MS. Both Certified Spiking Solutions are available in concentrations of 5 µg/mL in ethanol. Cerilliant also offers Snap-N-Spike reference standards of 25-Hydroxyvitamin D2 and 25-Hydroxyvitamin D3 including stable labeled 25-Hydroxyvitamin D3 for monitoring blood/serum calcidiol levels in determining vitamin D nutritional status.

Testing and interest in vitamin D levels have increased dramatically over the last few years as medical studies raise awareness of vitamin D deficiency and its impact on disease and overall health. A new report released in March, 2011, by the Institute of Medicine (IOM) found that around 25% of the US population were at risk of vitamin D inadequacy.

Starting with Cerilliant Certified Spiking Solutions provides flexibility in preparation of linearity standards, controls, or calibrators in the laboratory’s matrix of choice and eliminates weighing of sensitive and difficult compounds like vitamin D and its hydroxy metabolites. Preparation of Cerilliant Certified Spiking Solutions begins with full characterization of each raw material lot using an orthogonal approach. These solutions are gravimetrically prepared using a validated process and flame sealed under argon into ampoules for long-term shelf life. Solution accuracy, homogeneity, and shelf life are ensured though rigorous testing, which includes accelerated and real time studies.

Cerilliant Certified Spiking Solutions are prepared and certified to the highest industry standards including ISO Guide 34 and ISO 17025. Each reference solution is supported by a comprehensive Certificate of Analysis (COA), which provides all analytical data as well as uncertainty and traceability information for a laboratory’s regulatory requirements.

Source: Cerilliant