This family of EBV microplate ELISA test kits includes assays for EA-D IgG, VCA(p-18)IgG, VCA IgM, EBNA-1 IgG and EBNA-1 IgM. These assays can be used to determine an individual’s serologic EBV status and to aid in the diagnosis of infectious mononucleosis in adult populations.
The EA-D IgG assay is used for the qualitative determination of IgG antibodies to EA-D antigen in human serum. The assay uses a recombinant antigen that provides high sensitivity and specificity. When tested against clinically characterized sera, the EA-D IgG ELISA had a relative sensitivity of 100% with late acute sera and relative specificities of 100% and 97% in seronegative and early acute sera, respectively.
EVB VCA(p-18) and VCA IgM ELISA tests are intended for the qualitative determination of IgG and IgM antibodies to the Viral Capsid Antigen complex in human serum. The EBV VCA(p-18) IgG ELISA uses a recombinant antigen that provides for excellent sensitivity and specificity. When tested against clinically characterized sera, the VCA (p-18) IgG ELISA had a relative sensitivity of 95% with seropositive sera and a relative specificity of 97.4% with acute sera and relative specificities of 96.4% and 99% with seronegative and seropositive sera, respectively.
EBNA-1 IgM ELISA is intended for the qualitative determination of IgM antibodies in human serum to the EBNA-1 antigen. The EBNA-1 IgM ELISA uses a recombinant antigen that provides for a comparable degree of sensitivity and specificity and no cross reactivity with sera containing RF and VZV antibodies.
Wampole Laboratories
www.wampolelabs.com
Keyword: ELISA, assay, mononucleosis
