Summary:
Evident has launched the IXplore IX85 SpinXL and SpinSR, two advanced spinning disk confocal microscopes that enhance live-cell imaging through faster acquisition, wider views, and super-resolution capabilities.

Takeaways:

  1. SpinXL delivers fast, wide-field imaging with a 26.5 mm field number, ideal for capturing large sample areas and dynamic cellular events.
  2. SpinSR provides nanoscale detail using the TruSight SR algorithm for super-resolution imaging down to 120 nm, even in dim conditions.
  3. Both systems support gentle, real-time live-cell imaging and are designed for flexibility, scalability, and advanced 3D research applications.

Evident announces the release of two new spinning disk confocal microscopes, the IXplore IX85 SpinXL and the IXplore IX85 SpinSR. Built on Evident’s new IXplore IX85 automated inverted microscope system, the IX85 SpinXL and IX85 SpinSR add powerful new technology to the platform, expanding the possibilities of what researchers can capture and discover in live-cell imaging. 


IXplore IX85 SpinXL Offers a Wider View into Cellular Dynamics

Powered by CrestOptics X-Light spinning disk technology, the IXplore IX85 SpinXL offers an unparalleled 26.5 mm field number (FN) that enables users to quickly capture cellular dynamics and rapidly screen large areas. 

  • Its expansive FN coupled with a fast frame rate and dual camera capabilities enables the capture of more cellular dynamics in a single frame at imaging speeds up to 498 fps at full frame. 
  • Precise, gentle live-cell imaging supports sample viability and image consistency. A real-time controller delivers precisely coordinated imaging even at the highest speeds, reducing the risk of sample damage. 
  • NIR wavelengths offer deeper tissue penetration, reduced autofluorescence and crosstalk and gentler imaging for live tissues. 

The IX85 SpinXL streamlines tasks throughout the lab with intelligent automation and easy workflows. It supports many imaging applications and multiple users by balancing speed, precision and flexibility. The system is designed to evolve with research needs via a wide wavelength range, tailored disk options and expandable imaging modalities. 

IXplore IX85 SpinSR Empowers Faster Discovery in Stunning Detail

Powered by Yokogawa CSU-W1 spinning disk technology, the IXplore IX85 SpinSR super-resolution microscope enables users to capture ultra-small cellular dynamics in stunning detail. 

Designed for prolonged cell viability in time-lapse experiments, the system combines fast image acquisition, advanced algorithms and XY resolution down to 120 nm to accelerate 3D super-resolution imaging. Equipped with a real-time controller for precisely coordinated imaging, the system delivers fast, gentle live-cell imaging at the nanoscale. 
The IX85 SpinSR simplifies the capture of super-resolution details, empowering users to discover new insights faster. 

  • TruSight SR super-resolution algorithm enhances image resolution down to 120 nm with one click. It automatically optimizes the image processing filter based on the signal-to-noise ratio, enabling appropriate processing for live-cell imaging even in dim fluorescence conditions. 
  • TruSight SR preserves the original image’s intensity levels, enabling users to analyze and compare the brightness of samples in super-resolution images for quantitative analysis. 
  • Its 3D algorithm supports organoid research by delivering clear and precise super-resolution results, even deep inside samples. 

Both the IX85 SpinXL and IX85 SpinSR microscopes can be paired with the world’s first silicone gel pad objective (LUPLAPO25XS) for accurate 3D volumetric reconstruction and deeper focus into samples.

“We are excited to introduce two new spinning disk confocal microscopes to our IXplore IX85 series. Built on our stable IXplore IX85 platform and powered by advanced spinning disk technologies, the new SpinXL and SpinSR microscopes are designed to provide our customers with faster imaging that is extremely precise and gentle on live cells,” says Motoki Inoue, vice president, Product Management and Marketing, Life Science Research, Evident.  “With the new IX85 SpinXL microscope, users can take advantage of an unparalleled 26.5 mm field number to reduce imaging time for large sample sets. This wider view enables the capture of more cellular dynamics in a single frame, supporting faster data acquisition. The new IX85 SpinSR microscope introduces the TruSight SR algorithm for stunning super-resolution detail at speed—critical for customers who need to observe ultra-small cellular dynamics.”  

Featured Image:  The IXplore IX85 SpinXL offers an unparalleled 26.5 mm field number (FN) that enables users to quickly capture cellular dynamics and rapidly screen large areas. Image: Evident