A new test from Thermo Fisher Scientific, Kalamazoo, Mich, helps allergists and other medical providers better predict which patients may be at risk for life-threatening sensitization to Ara h 6, a protein component in peanuts that can cause severe allergic reactions in certain individuals. 

Thermo Fisher’s ImmunoCap Specific IgE blood test for Ara h 6, part of a line of assays for detecting specific peanut allergen components, has been cleared by FDA for in vitro diagnostic use. 

Results from Ara h 6 ImmunoCap testing can act as an aid to help specialists and other clinicians better understand patients’ risk factors as part of tailored allergy treatment or management plans. In some cases, ImmunoCap testing may reduce the need for oral food challenges, a testing method where a healthcare professional feeds a patient food in measured doses to see if it triggers an allergic reaction. 

“Testing a patient’s sensitivity to Ara h 6 can play a critical role in understanding the likelihood of a future life-threatening reaction,” says Rebecca Rosenberger, MMSc, PA-C, senior manager for clinical affairs and education at Thermo Fisher Scientific. “Adding the Ara h 6 test to the existing ImmunoCap peanut component assays enables us to provide a more complete view of a patient’s overall peanut sensitization, including whether a patient is at risk for cross-reactivity.” 

Advanced diagnostic capabilities for peanut allergies can contribute to better outcomes for allergy sufferers, especially young children. Patients should consult with their healthcare provider to get tested for individual peanut components. Such knowledge helps the clinician understand potential risks, leads to more informed allergy management, and provides renewed peace of mind for patients and parents. 

The newest addition to the ImmunoCap line of component allergy tests also includes assays for cross-reactive carbohydrate determinants (CCD) and profilins, which are both allergens contained in various plants, pollens, and foods. Sensitization to CCD or profilin usually does not cause any symptoms but is due to cross-reactivity with certain plants and pollens. 

ImmunoCap testing is the most widely used specific IgE blood test, and its accuracy has been documented in more than 4,000 peer-reviewed publications. The tests can identify allergic sensitization to common environmental allergens—seasonal and perennial, indoor and outdoor—as well as common food allergies such as peanuts, eggs, and milk. ImmunoCap tests, which are available in most major US laboratories, can be ordered for patients of any age regardless of skin condition, current medication, symptom, disease activity, or pregnancy status. 

For further information, visit Thermo Fisher Scientific. 

 

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