This company has introduced an immunoturbidimetric assay for the measurement of ultra sensitive C-Reative Protein (CRP). This version of the CRP assay has several potential clinical applications; recent publications have shown that sensitive CRP can help assess cardiovascular risk.
Studies suggest that CRP levels greater than 2mg/L indicate increased cardiovascular risk. The pathogenesis of arterial thrombosis has been linked to an inflammatory process, which can lead to elevated CRP levels. The inflammatory reaction causes small changes in CRP levels and an ultra sensitive CRP assay can detect these changes.
The latex-enhanced immunoturbidimetric technology measures the increased turbidity (at 550nm) resulting from antibody-antigen complexes formed when sample and antibody reagent are mixed. By constructing a standard curve from the absorbance of standards, CRP concentrations of sample can be determined.
The assay has sensitivity of .05mg/L, and the company offers a choice of two assays, measuring ranges 0-5mg/L and 0-15mg/L. These tests for CRP ultra sensitive go directly on the chemistry analyzer and yield quantitative results. Application parameters are available for several chemistry analyzers.
keyword: reagent, cardiac, CRP