The BioSpa live cell imaging system from BioTek Instruments, Winooski, Vt, fully automates live cell imaging workflows for robust, real-time results without the need for manual intervention. The BioSpa system has a compact footprint for use on benchtops and in biosafety cabinets, and consists of the BioSpa 8 automated incubator and Cytation 5 cell imaging multimode reader. BioTek’s liquid handling instruments may also be linked to the BioSpa system for complete walkaway automation from sample preparation through image analysis. BioSpa 8 provides precise, real-time environmental control and monitoring for live cell assays in up to eight lidded or unlidded plates or other labware. It incorporates a robotic gripper to move sample plates or vessels from BioSpa 8’s incubator drawer to Cytation 5 for automated image capture, processing, and quantitative analysis of live cell assays. Imaging capabilities include fluorescence, brightfield, color brightfield, and phase contrast, up to 60x, along with such advanced imaging and analysis features as digital phase contrast, image stitching, montage creation, single or multicolor imaging, time lapse, video creation, and Z-stacking and Z-projection. For more information, visit BioTek Instruments.