Summary: GenomOncology announced enhancements to its Pathology Workbench software, which features improved support for germline and somatic testing.
Takeaways:
- The latest update to the GO Pathology Workbench includes expanded germline testing capabilities that enable labs to perform more precise and comprehensive genetic analyses.
- The software allows molecular laboratories to analyze and report on any NGS test through a singular, unified workflow.
- The GO Pathology Workbench features support for everything from quality control review to the automation of variant classification and matching of cancer patients to clinical trials.
GenomOncology (GO) unveiled an upgraded version of GO Pathology Workbench, the company’s software platform for tertiary analysis and reporting of next generation sequencing (NGS) and other molecular testing results.
Improved Germline Testing Capabilities
This updated version includes expanded support for germline testing, reinforcing its capacity to conduct tertiary analysis across all assays, ranging from tumor sequencing, hereditary cancer, rare diseases, and all somatic and germline panels through whole genome analysis, the company says. These advancements optimize processes within molecular laboratories, empowering them to seamlessly analyze and report any NGS test in a singular, unified workflow.
The expanded support for germline testing includes additional variant annotations, including the FDA-recognized ClinGen database. This release also includes full support for the American College of Medical Genetics (ACMG) classification system, including automatic variant classification based on ClinGen, a seamless loading process for any existing laboratory’s classifications, and an efficient ACMG worksheet tailored for novel variants. The solution includes additional features that enhance the efficiency of whole exome and whole genome sequencing analysis, resulting in a single comprehensive solution that delivers high-quality, efficient tertiary analysis and reporting across a molecular laboratory’s NGS testing menu.
Upgraded Pathology Workbench
The upgrades to GO Pathology workbench for germline testing complement the best-in-class analysis of somatic testing. GO Pathology Workbench is an end-to-end tertiary analysis solution that streamlines quality control review, automates variant classification and tiering using the AMP/ASCO/CAP somatic tiering system, matches cancer patients to the most relevant clinical trials and therapies, and produces a fully customizable report.
“The latest enhancements to GO Pathology Workbench for germline testing will empower laboratories to interpret and report their entire NGS test menu using a single application, with all cases in a shared worklist and database,” says Matt Stachowiak, VP of product innovation at GenomOncology. “This will increase efficiency, as well as enable creative approaches to reporting somatic and germline results for the same patient.”
Further reading: GenomOncology Releases IgniteIQ Data Extraction Solution
