Laboratory Corp of America Holdings, Burlington, NC, is offering a high-density microarray, Affymetrix-based technology (Whole-Genome Sampling Analysis).

The testing offers resolution for detection of the etiology of mental retardation, developmental delay, autism, and other clinically significant changes.

In 2005, the company offered the comparative genomic hybridization-based microarray diagnostics, which focused on mental retardation and developmental delay. The targeted testing underscored the need for higher density whole-genome coverage.

The new technology provides analysis of DNA copy number changes—identifying deletions, gene amplifications, and loss of heterozygosity.