CytoSmart Technologies, Eindhoven, the Netherlands, has released its first fluorescence cell counter. The CytoSmart Exact FL is an automated, dual fluorescence cell counter with an expanded field of view and enhanced performance.

Although the system’s footprint is very small, the company says its specifications rival most, if not all, alternative automated cell counters. The CytoSmart Exact FL provides enhanced accuracy, speed, and performance thanks to a wide range of technological advancements. The improved specifications include not only an advanced 6.4-megapixel CMOS camera, but also ultrafast autofocus, high magnification and high contrast lenses, increased measuring volume, and super robust image recognition using artificial intelligence (AI) algorithms. 

The CytoSmart Exact FL calculates the exact number of cells in a sample and provides a reliable assessment of key cellular parameters, including cell viability and transfection efficiency. The increased magnification and high resolution offer an exceptional level of detail, distinguishing between whole cells and cell debris and counting even the smallest of mammalian cells (CAR-T cells, stem cells, PBMCs). 

“We are truly excited to launch this dual fluorescence cell counter with an optical system of unmatched power,” says Joffry Maltha, CEO at CytoSmart Technologies. “This innovative device can be used for a number of standard laboratory applications. The CytoSmart Exact FL can count cells using a bright-field channel, while simultaneously assessing viability and transfection efficiency with two fluorescent channels. It can also ease the counting of hard-to-detect primary cells or quantify multiple cell types in one sample. Another fascinating feature of our devices is the introduction of add-on modules, which enable customers to expand the application range of their device, allowing them to also count organoids.” – 

The main features and advantages of the CytoSmart Exact FL include:

  • 6.4 Megapixel camera
  • High contrast and high magnification optics
  • Ultrafast autofocus
  • Dual fluorescence cell counting
  • AI-powered image analysis software
  • Lower coefficient of variation with increased counting volume option and a multi-count feature
  • Ability to add organoid counting module
  • Very cost efficient thanks to its compatibility with reusable or disposable counting slides
  • Secure cloud data storage

For more information, visit CytoSmart. 

Featured image: CytoSmart Exact FL fluorescence cell counter (Courtesy: CytoSmart).