Amsbio, Abingdon, UK, has introduced StemFit for Differentiation, a chemically defined and animal component-free formulation that enables unmatched differentiation of human Induced pluripotent stem (hiPS) and embryonic stem (hES) cells.

The unique chemically defined composition of StemFit for Differentiation minimizes lot-to-lot variation, enabling highly consistent cell differentiation. Free of animal- and human-derived components, StemFit for Differentiation can be used to eliminate the risk of immunogenic contamination.

Applications proven to benefit from StemFit for Differentiation include lineage-specific (endodermal, mesodermal, and ectodermal) differentiation where this product is used to replace serum-free supplements as well as spontaneous differentiation of hiPSCs to organoids via embryoid body formation.

Used in combination with StemFit Basic feeder-free medium with iMatrix-511 laminin as extracellular matrix, StemFit for Differentiation enables researchers to undertake clinical applications involving both expansion and differentiation of human pluripotent stem cell-derived cells and tissues.

Supplied as a 5X concentrate, StemFit for Differentiation has been formulated for use with basal cell culture medium (for example, DMEM, RPMI 1640, DMEM/F12) and a variety of different induction factors or cytokines (including Activin A and bFGF from Amsbio).

For more information, visit Amsbio.