Large Melanoma Trial Validates Gene Expression Test’s Predictive Accuracy
A study of nearly 1,800 patients shows a threefold difference in sentinel node metastasis rates between high-risk and low-risk groups.
Category: Cancer
Cancer
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Cancer
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Genetic Test Now Available to Predict Radiation Therapy Side Effects in Prostate Cancer
PROSTOX ultra identifies patients at higher risk of developing late genitourinary toxicity from stereotactic body radiation therapy.
Cancer
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Why Closing Lung Cancer’s Diagnostic Gap Will Require New Lab Strategies
On World Lung Day, Reveal Dx board member Mat Brevard discusses why current diagnostic tools fall short—and how new approaches could improve accuracy and outcomes.Â
Circulating Tumor DNA Shows Promise for Guiding Immunotherapy in Lung Cancer
Study of 177 patients with limited-stage small cell lung cancer demonstrates ctDNA’s potential to personalize consolidation immunotherapy decisions.
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Genomic Test Shows Promise for Guiding Chemotherapy Decisions in Metastatic Prostate Cancer
Phase 3 STAMPEDE trial data demonstrates Decipher Prostate test can predict docetaxel treatment benefit, potentially helping patients avoid unnecessary toxicity.
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Personalis MRD Test Shows Superior Sensitivity in Lung Cancer Trial
The test demonstrated higher baseline sensitivity for ctDNA detection compared to gene mutation-based testing in AstraZeneca’s NeoADAURA study.
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Cerebrospinal Fluid Test Identifies Brain Cancers with 100% Specificity
Johns Hopkins researchers develop multi-analyte assay combining tumor DNA, mutations, and immune cell signatures for central nervous system cancer diagnosis.
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FDA Grants De Novo Authorization for AI-Powered Prostate Cancer Prognostic Software
The risk stratification tool is designed to predict long-term outcomes for patients with non-metastatic prostate cancer.
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VieCure Adds Summit Cancer Centers to Community Oncology Network
Multi-disciplinary cancer center will implement Halo Intelligence platform to enhance precision oncology capabilities across Pacific Northwest.
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Ultrasensitive MRD Test Shows Greater Prognostic Accuracy Than PET/CT in Lymphoma
Pooled analysis of 137 patients shows the assay achieved 86% sensitivity and 91% specificity for relapse detection in large B-cell lymphoma, leading to NCCN guideline inclusion.
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Blood Test Achieves 85% Accuracy in Predicting Breast Cancer Immunotherapy Response
Researchers develop PIPscore using plasma proteomics to identify triple-negative breast cancer patients most likely to benefit from immunotherapy treatment.
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Mass General Brigham Launches Trials of Blood Test to Guide Post-Surgery Cancer Care
Two studies will evaluate circulating tumor DNA as a guide for post-surgical cancer treatment decisions.
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Colorectal Cancer Screening Surges 62% Among Adults 45-49, Driving Early-Stage Diagnoses
Two new American Cancer Society studies reveal significant increases in colorectal cancer...
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Three Boston Institutions Launch Precision Genomics Initiative for Pediatric Cancer Testing
Dana-Farber Cancer Institute, Boston Children’s Hospital, and Broad Clinical Labs form BrightSeq collaborative to develop novel clinical diagnostic assays for rare pediatric cancers.
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At-Home Cervical Cancer Screening Now Available, Starting in California
This marks the first time a US Food and Drug Adminstration-authorized self-collection device is available for at-home cervical cancer screening in the US.
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Test Gains Medicare Coverage for Early-Stage Breast Cancer Recurrence Monitoring
Coverage marks a step in expanding access to ultra-sensitive molecular residual disease detection for breast cancer patients.
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CyPath Lung Flags Early-Stage Cancer Overlooked by Previous Tests
A case study shows how the noninvasive test detected Stage 1A mucinous adenocarcinoma in a high-risk patient whose previous tests and follow-up scans had suggested a low probability of cancer.
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Declining Cancer Screening Rates Prompt Interest in New Detection Methods
A survey indicates a decline in cancer screening rates, contrasted by growing interest in at-home and multi-cancer early detection tests.
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