Category: Disease States

Disease States

Alternative Blood Test More Effective for Guiding Heart Disease Treatment

Research indicates that apolipoprotein B testing outperforms standard LDL cholesterol tests in predicting risk and guiding therapy.

Disease States

DecisionDx-Melanoma Gene Expression Test Improves Risk Prediction Beyond Standard Staging

Data from nearly 1,900 SEER-linked patients show the test identifies meaningful survival differences within the same AJCC stage.

Disease States

Diabetes Testing Moves Earlier—and Gets More Complex

As the 2026 ADA Standards of Care emphasize earlier identification and more precise classification of diabetes, clinical laboratories are rethinking workflows, assay menus, and their role in detection.

Cancer

Urine-Based Liquid Biopsy Shows High Sensitivity for Prostate Cancer Detection

A new study validates a machine-learning platform that detects prostate cancer through biochemical patterns in urine samples.

Infectious Diseases

Blood Test May Improve Risk Assessment for HPV-Related Throat Cancer

Research identifies how circulating tumor DNA can inform personalized treatment and surveillance strategies.

Womens Health

NIH Awards $850,000 to Support Menstrual Blood Test for Endometriosis

The NIH has awarded $850,000 to Northwell Health’s Feinstein Institutes to advance a noninvasive menstrual blood test for endometriosis, aiming to reduce reliance on surgical diagnosis, according to the institutes.

Allergy & Autoimmune

Skin Patch Opens New Door for Immune Monitoring

Researchers at JAX and MIT have developed a microneedle patch that samples immune cells from skin within hours, providing a noninvasive alternative to blood draws and biopsies.

Cardiovascular, Cerebrovascular

Updated Guideline Issued on Lipid and Cholesterol Management, Expanding Role of Key Biomarker Tests

The ACC, AHA, and nine other associations have issued an updated dyslipidemia guideline, recommending earlier intervention and expanded use of lipoprotein(a) and apolipoprotein B testing to improve cardiovascular risk assessment.

Dementias & Alzheimer’s

Gut-Derived Blood Markers May Detect Early Cognitive Decline Before Symptoms

Researchers at the University of East Anglia report that gut-derived blood markers may help detect early cognitive decline before symptoms, according to findings published in Gut Microbes.

Diabetes & Metabolic Diseases

New Blood Test Score Identifies Hidden Alcohol-Related Liver Disease

Researchers at UC San Diego have developed the MAPI score, a blood test using five standard lab values to distinguish alcohol-related liver injury from metabolic causes, according to a study in Gastroenterology.

Kidney Disease

Insight Molecular Diagnostics Nears FDA Submission for Kidney Transplant Rejection Test Kit

Insight Molecular Diagnostics has completed clinical validation and received ISO 13485 certification for its GraftAssureDx kidney transplant rejection test kit, moving toward FDA submission, according to the company.

Respiratory Disease

Yourgene Health Cystic Fibrosis Assay Receives IVDR Accreditation

The Cystic Fibrosis Base assay has received IVDR accreditation, ensuring high standards for detecting cystic fibrosis mutations.

Sepsis

Sepsis Diagnostic Test Shapes ED Physician Decision-Making, Study Finds

A multicenter, vignette-based study found that adding a rapid sepsis test result to standard clinical data changed or reinforced diagnostic decisions in 86% of cases.